| Literature DB >> 1255065 |
C N Trotman, I J Fiddes, E R Grund, S McHanwell, D J Sanders, C Sanderson, B Shaw.
Abstract
Immunoreactive gastrin was measured in subcellular fractions of rat gastric mucosa. The sedimentational properties of subcellular gastrin-containing structures were distinct from those of mitochondria. After centrifugation in sucrose density gradients using a zonal rotor, the peak of immunoreactive gastrin was found in 1-17--1-18 g cm(-3) density sucrose (1-35 M; 39-5%, W/W). A thermolabile component with 125I-labelled gastrin-binding activity present in gastric mucosal homogenates and fractions was not associated with the gastrin storage vesicles sedimenting in density gradients.Entities:
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Year: 1976 PMID： 1255065 DOI： 10.1677/joe.0.0680005
Source DB: PubMed Journal: J Endocrinol ISSN： 0022-0795 Impact factor: 4.286