| Literature DB >> 1254644 |
J M Oliver, J A Krawiec, R D Berlin.
Abstract
Primary embryonic fibroblasts isolated from beige (Chediak-Higashi) mice develop pathognomonic giant granules in vitro. Inclusion in the culture medium of carbamylcholine (carbachol) or phorbol myristate acetate (PMA) results in the generation of morphologically normally granules. Chediak-Higashi fibroblasts are highly susceptible to shape changes induced by colchicine. This abnormal property is also corrected by carbachol and PMA.Entities:
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Year: 1976 PMID: 1254644 PMCID: PMC2110978 DOI: 10.1083/jcb.69.1.205
Source DB: PubMed Journal: J Cell Biol ISSN: 0021-9525 Impact factor: 10.539