Literature DB >> 1254322

Evidence for the secretory transport mechanism of intestinal immunoglobulin. The ultrastructural distribution of IgM.

W D Allen, C G Smith, P Porter.   

Abstract

The intracellular localization of IgM in porcine intestinal tissue has been studied by immunoelectron microscopy and immunofluorescence. IgM was demonstrated in vesicles in the cytoplasm of crypt epithelial cells particularly in the supranuclear region. It was also shown in the ergastoplasmic cisternae of plasma cells in the intercryptal lamina propria. The findings are compared with those of a previous similar study on secretory IgA and their implications for possible mechanisms of selective transport are discussed.

Mesh：

Substances：

Year:  1976        PMID： 1254322      PMCID： PMC1445161     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  16 in total

1.  The relative distribution of IgM and IgA cells in intestinal mucosa and lymphoid tissues of the young unweaned pig and their significance in ontogenesis of secretory immunity.

Authors:  W D Allen; P Porter
Journal:  Immunology       Date:  1973-03       Impact factor: 7.397

2.  Intestinal secretion of immunoglobulins and antibodies to Escherichia coli in the pig.

Authors:  P Porter; D E Noakes; W D Allen
Journal:  Immunology       Date:  1970-06       Impact factor: 7.397

3.  Immunoglobulin M: local synthesis and selective secretion in patients with immunoglobulin A deficiency.

Authors:  P Brandtzaeg; I Fjellanger; S T Gjeruldsen
Journal:  Science       Date:  1968-05-17       Impact factor: 47.728

4.  Immunoglobulin content of intestinal mucosal plasma-cells in ataxia telangiectasia.

Authors:  S Eidelman; S D Davis
Journal:  Lancet       Date:  1968-04-27       Impact factor: 79.321

5.  Localization of immunoglobulins in intestinal mucosa and the production of secretory antibodies in response to intraluminal administration of bacterial antigens in the preruminant calf.

Authors:  W D Allen; P Porter
Journal:  Clin Exp Immunol       Date:  1975-09       Impact factor: 4.330

6.  Does J chain mediate the combination of 19S IgM and dimeric IgA with the secretory component rather than being necessary for their polymerization?

Authors:  T Eskeland; P Brandtzaeg
Journal:  Immunochemistry       Date:  1974-03

7.  Intestinal secretion of immunoglobulins in the preruminant calf.

Authors:  P Porter; D E Noakes; W D Allen
Journal:  Immunology       Date:  1972-09       Impact factor: 7.397

8.  Immunoglobulins in bovine mammary secretions. Quantitative changes in early lactation and absorption by the neonatal calf.

Authors:  P Porter
Journal:  Immunology       Date:  1972-08       Impact factor: 7.397

9.  Preparation and characterization of an immuno-electron microscope tracer consisting of a heme-octapeptide coupled to fab.

Authors:  J P Kraehenbuhl; R E Galardy; J D Jamieson
Journal:  J Exp Med       Date:  1974-01-01       Impact factor: 14.307

10.  The human secretory immunoglobulin system: immunohistoligical localization of gamma A, secretory "piece," and lactoferrin in normal human tissues.

Authors:  D R Tourville; R H Adler; J Bienenstock; T B Tomasi
Journal:  J Exp Med       Date:  1969-02-01       Impact factor: 14.307
View more
  2 in total

1.  The relative frequencies and distribution of immunoglobulin-bearing cells in the intestinal mucosa of neonatal and weaned pigs and their significance in the development of secretory immunity.

Authors:  W D Allen; P Porter
Journal:  Immunology       Date:  1977-05       Impact factor: 7.397

2.  Serum protein content of rat small-intestinal mucus.

Authors:  B E Lukie
Journal:  Dig Dis Sci       Date:  1986-01       Impact factor: 3.199
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.