Literature DB >> 12542354

Chemical and biological investigation of the fungus Pulveroboletus ravenelii.

Christine J G Duncan1, Muriel Cuendet, Frank R Fronczek, John M Pezzuto, Rajendra G Mehta, Mark T Hamann, Samir A Ross.   

Abstract

Two new compounds, pulveraven A (1) and pulveraven B (2), as well as vulpinic acid (3) and its previously unreported polymorph were isolated from the fruiting body of Pulveroboletus ravenelii. The structures were determined using a combination of NMR, MS, IR, optical rotation, molecular modeling, and X-ray analysis. The isolates were evaluated for antimicrobial activity as well as their potential to inhibit cyclooxygenase (COX) activity and carcinogen-induced preneoplastic lesion formation with mouse mammary organ culture (MMOC).

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Year:  2003        PMID: 12542354      PMCID: PMC4969011          DOI: 10.1021/np0203990

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  4 in total

1.  Note on the action of vulpinic acid.

Authors:  U SODERBERG
Journal:  Acta Physiol Scand       Date:  1952

Review 2.  The role of cyclooxygenase and lipoxygenase in cancer chemoprevention.

Authors:  M Cuendet; J M Pezzuto
Journal:  Drug Metabol Drug Interact       Date:  2000

3.  Vulpinic acids as potential antiinflammatory agents. 1. Vulpinic acids with substituents in the aromatic rings.

Authors:  F R Foden; J McCormick; D M O'Mant
Journal:  J Med Chem       Date:  1975-02       Impact factor: 7.446

4.  Influence of thiols and inhibitors of prostaglandin biosynthesis on the carcinogen-induced development of mammary lesions in vitro.

Authors:  R G Mehta; V Steele; G J Kelloff; R C Moon
Journal:  Anticancer Res       Date:  1991 Mar-Apr       Impact factor: 2.480

  4 in total
  2 in total

1.  Potential of lichen secondary metabolites against Plasmodium liver stage parasites with FAS-II as the potential target.

Authors:  Ina L Lauinger; Livia Vivas; Remo Perozzo; Christopher Stairiker; Alice Tarun; Mire Zloh; Xujie Zhang; Hua Xu; Peter J Tonge; Scott G Franzblau; Duc-Hung Pham; Camila V Esguerra; Alexander D Crawford; Louis Maes; Deniz Tasdemir
Journal:  J Nat Prod       Date:  2013-06-19       Impact factor: 4.050

2.  Direct enantioselective conjugate addition of carboxylic acids with chiral lithium amides as traceless auxiliaries.

Authors:  Ping Lu; Jeffrey J Jackson; John A Eickhoff; Armen Zakarian
Journal:  J Am Chem Soc       Date:  2015-01-08       Impact factor: 15.419

  2 in total

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