| Literature DB >> 12542349 |
Hyuncheol Oh1, Dale C Swenson, James B Gloer, Carol A Shearer.
Abstract
Four new rosigenin analogues (massarigenins A-D; 1-4) and two new aromatic polyketide-derived secondary metabolites (massarinins A and B; 6, 7) and have been isolated from the freshwater aquatic fungus Massarina tunicata. The structures of these compounds were determined primarily by analysis of NMR data, and that of compound 1 was verified by X-ray crystallography. The known compound 4-(2-hydroxybutynoxy)benzoic acid (11) was also obtained, and its absolute stereochemistry was assigned. Several of these metabolites showed antibiotic activity against Gram-positive bacteria.Entities:
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Year: 2003 PMID: 12542349 DOI: 10.1021/np020342d
Source DB: PubMed Journal: J Nat Prod ISSN: 0163-3864 Impact factor: 4.050