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Literature DB >> 12542346

Novel chromone derivatives from the fungus Aspergillus versicolor isolated from the marine sponge Xestospongia exigua.

Wenhan Lin¹, Gernot Brauers, Rainer Ebel, Victor Wray, Albrecht Berg, Peter Proksch.

Abstract

From the marine sponge Xestospongia exigua collected in Indonesia the fungus Aspergillus versicolor was isolated. Following cultivation in a seawater-based medium seven new angular tricyclic chromone derivatives (1-7) were obtained from the mycelia and culture filtrate. Compounds 2-7 contain an additional dihydropyran ring system which is replaced by a pyridine ring in 1. The structures of the new natural products were established on the basis of extensive one- and two-dimensional NMR spectroscopic studies (1H, 13C, COSY, HMQC, HMBC, NOE difference spectra) as well as on mass spectral analysis.

Entities: Chemical Species

Mesh：

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Year: 2003 PMID： 12542346 DOI： 10.1021/np020196b

Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050

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Cited

12 in total

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4. Recovery and phylogenetic diversity of culturable fungi associated with marine sponges Clathrina luteoculcitella and Holoxea sp. in the South China Sea.

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Journal: Mar Biotechnol (NY) Date: 2010-11-19 Impact factor: 3.619

10. A tropical marine microbial natural products geobibliography as an example of desktop exploration of current research using web visualisation tools.

Authors: Joydeep Mukherjee; Lyndon E Llewellyn; Elizabeth A Evans-Illidge
Journal: Mar Drugs Date: 2008-10-13 Impact factor: 5.118

Novel chromone derivatives from the fungus Aspergillus versicolor isolated from the marine sponge Xestospongia exigua.

1. Methods for isolation of marine-derived endophytic fungi and their bioactive secondary products.

Review 2. Survey of marine natural product structure revisions: a synergy of spectroscopy and chemical synthesis.

3. Efficient Pathway for the Preparation of Aryl(isoquinoline)iodonium(III) Salts and Synthesis of Radiofluorinated Isoquinolines.

4. Recovery and phylogenetic diversity of culturable fungi associated with marine sponges Clathrina luteoculcitella and Holoxea sp. in the South China Sea.

Review 5. Marine drugs from sponge-microbe association--a review.

Review 6. The current status of natural products from marine fungi and their potential as anti-infective agents.

7. Pharmacophore-Based Virtual Screening of Novel Inhibitors and Docking Analysis for CYP51A from Penicillium italicum.

8. Diversity of Marine-Derived Aspergillus from Tidal Mudflats and Sea Sand in Korea.

9. Orthogonal Method for Double-Bond Placement via Ozone-Induced Dissociation Mass Spectrometry (OzID-MS).

10. A tropical marine microbial natural products geobibliography as an example of desktop exploration of current research using web visualisation tools.