Literature DB >> 12541017

Is a bilateral modified radical neck dissection beneficial for patients with papillary thyroid cancer?

Akira Ohshima1, Hiroyuki Yamashita, Shiro Noguchi, Shinya Uchino, Shin Watanabe, Eisuke Koike, Hiroto Yamashita, Syoji Kuroki, Masao Tanaka.   

Abstract

PURPOSE: We previously reported a poor prognosis in papillary thyroid carcinoma patients with recurrence in the contralateral cervical lymph nodes after thyroidectomy and ipsilateral modified radical neck dissection (MRND) with a curative intent. The aim of this study was to investigate whether bilateral MRND improved prognosis in patients at risk for contralateral nodal recurrence.
METHODS: We retrospectively reviewed the cases of 86 patients with contralateral nodal metastasis who underwent a thyroidectomy with bilateral MRND (group 1) and the cases of 32 patients who suffered contralateral nodal recurrence after a thyroidectomy with ipsilateral MRND (group 2).
RESULTS: Although tumor progression was considered similar in patients from groups 1 and 2, group 1 developed fewer distant metastases than group 2 (6.8% vs 31.1%), thus resulting in a lower cancer death rate (5.8% vs 28.1%). Group 1 had a better 10-year survival rate than of group 2 (97.1% vs 83.7%).
CONCLUSION: Bilateral MRND during initial surgical management is thus considered to improve the prognosis of some papillary carcinoma patients at risk for recurrence in the contralateral cervical lymph nodes.

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Year:  2002        PMID: 12541017     DOI: 10.1007/s005950200208

Source DB:  PubMed          Journal:  Surg Today        ISSN: 0941-1291            Impact factor:   2.549


  3 in total

1.  Risk factors for local recurrence following lateral neck dissection for papillary thyroid carcinoma.

Authors:  Marco Raffaelli; Carmela De Crea; Luca Sessa; Serena Elisa Tempera; Amanda Belluzzi; Celestino P Lombardi; Rocco Bellantone
Journal:  Endocrine       Date:  2018-10-19       Impact factor: 3.633

2.  Outcome of patients surgically treated for various forms of hyperthyroidism with differentiated thyroid cancer: experience at an endocrine center in Italy.

Authors:  Carlo Cappelli; Marco Braga; Elvira De Martino; Maurizio Castellano; Elena Gandossi; Barbara Agosti; Davide Cumetti; Ilenia Pirola; Chiara Mattanza; Laura Cherubini; Enrico Agabiti Rosei
Journal:  Surg Today       Date:  2006       Impact factor: 2.549

3.  Identifying risk factors for recurrence of papillary thyroid cancer in patients who underwent modified radical neck dissection.

Authors:  Young Jae Ryu; Jin Seong Cho; Jung Han Yoon; Min Ho Park
Journal:  World J Surg Oncol       Date:  2018-10-12       Impact factor: 2.754

  3 in total

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