Literature DB >> 12540920

The digital code of DNA.

Leroy Hood1, David Galas.   

Abstract

The discovery of the structure of DNA transformed biology profoundly, catalysing the sequencing of the human genome and engendering a new view of biology as an information science. Two features of DNA structure account for much of its remarkable impact on science: its digital nature and its complementarity, whereby one strand of the helix binds perfectly with its partner. DNA has two types of digital information--the genes that encode proteins, which are the molecular machines of life, and the gene regulatory networks that specify the behaviour of the genes.

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Year:  2003        PMID: 12540920     DOI: 10.1038/nature01410

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  31 in total

Review 1.  Human cardiac systems electrophysiology and arrhythmogenesis: iteration of experiment and computation.

Authors:  Katherine M Holzem; Eli J Madden; Igor R Efimov
Journal:  Europace       Date:  2014-11       Impact factor: 5.214

2.  Fractal analysis in a systems biology approach to cancer.

Authors:  M Bizzarri; A Giuliani; A Cucina; F D'Anselmi; A M Soto; C Sonnenschein
Journal:  Semin Cancer Biol       Date:  2011-04-13       Impact factor: 15.707

3.  Detecting distant homology with Meta-BASIC.

Authors:  Krzysztof Ginalski; Marcin von Grotthuss; Nick V Grishin; Leszek Rychlewski
Journal:  Nucleic Acids Res       Date:  2004-07-01       Impact factor: 16.971

Review 4.  Charting gene regulatory networks: strategies, challenges and perspectives.

Authors:  Gong-Hong Wei; De-Pei Liu; Chih-Chuan Liang
Journal:  Biochem J       Date:  2004-07-01       Impact factor: 3.857

5.  A hyperspace model to decipher the genetic architecture of developmental processes: allometry meets ontogeny.

Authors:  Rongling Wu; Wei Hou
Journal:  Genetics       Date:  2005-09-12       Impact factor: 4.562

Review 6.  The expanding transcriptome: the genome as the 'Book of Sand'.

Authors:  Luis M Mendes Soares; Juan Valcárcel
Journal:  EMBO J       Date:  2006-03-02       Impact factor: 11.598

7.  The principle of recursive genome function.

Authors:  Andras J Pellionisz
Journal:  Cerebellum       Date:  2008       Impact factor: 3.847

8.  Biological Information as Set-Based Complexity.

Authors:  David J Galas; Matti Nykter; Gregory W Carter; Nathan D Price; Ilya Shmulevich
Journal:  IEEE Trans Inf Theory       Date:  2010-02-25       Impact factor: 2.501

9.  The role of self-organization in developmental evolution.

Authors:  Joseph E Hannon Bozorgmehr
Journal:  Theory Biosci       Date:  2014-04-16       Impact factor: 1.919

10.  Nature's reach: narrow work has broad impact.

Authors:  Alexander J Gates; Qing Ke; Onur Varol; Albert-László Barabási
Journal:  Nature       Date:  2019-11       Impact factor: 49.962

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