Literature DB >> 12540744

Trafficking of NMDA receptors.

Robert J Wenthold1, Kate Prybylowski, Steve Standley, Nathalie Sans, Ronald S Petralia.   

Abstract

The NMDA receptor (NMDAR) plays a central role in the function of excitatory synapses. Recent studies have provided interesting insights into several aspects of the trafficking of this receptor in neurons. The NMDAR is not a static resident of the synapse. Rather, the number and composition of synaptic NMDARs can be modulated by several factors. The interaction of PDZ proteins, generally thought to occur at the synapse, appears to occur early in the secretory pathway; this interaction may play a role in the assembly of the receptor complex and its exit from the endoplasmic reticulum. This review addresses recent advances in our understanding of NMDAR trafficking and its synaptic delivery and maintenance.

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Year:  2002        PMID： 12540744     DOI： 10.1146/annurev.pharmtox.43.100901.135803

Source DB:  PubMed          Journal:  Annu Rev Pharmacol Toxicol        ISSN： 0362-1642            Impact factor:   13.820


  135 in total

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2.  The novel antipsychotic drug lurasidone enhances N-methyl-D-aspartate receptor-mediated synaptic responses.

Authors:  Eunice Y Yuen; Xiangning Li; Jing Wei; Masakuni Horiguchi; Herbert Y Meltzer; Zhen Yan
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Authors:  Gabriela Lavezzari; Jennifer McCallum; Colleen M Dewey; Katherine W Roche
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Review 4.  Synaptic neurotransmitter-gated receptors.

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Review 5.  NMDA receptors and metaplasticity: mechanisms and possible roles in neuropsychiatric disorders.

Authors:  Charles F Zorumski; Yukitoshi Izumi
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Review 6.  Development and critical period plasticity of the barrel cortex.

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Review 7.  Glutamate receptor ion channels: structure, regulation, and function.

Authors:  Stephen F Traynelis; Lonnie P Wollmuth; Chris J McBain; Frank S Menniti; Katie M Vance; Kevin K Ogden; Kasper B Hansen; Hongjie Yuan; Scott J Myers; Ray Dingledine
Journal:  Pharmacol Rev       Date:  2010-09       Impact factor: 25.468

8.  Novel approach to probe subunit-specific contributions to N-methyl-D-aspartate (NMDA) receptor trafficking reveals a dominant role for NR2B in receptor recycling.

Authors:  Tina Tze-Tsang Tang; John D Badger; Paul A Roche; Katherine W Roche
Journal:  J Biol Chem       Date:  2010-04-28       Impact factor: 5.157

9.  Identification of Novel 14-3-3 Residues That Are Critical for Isoform-specific Interaction with GluN2C to Regulate N-Methyl-D-aspartate (NMDA) Receptor Trafficking.

Authors:  Connie Chung; Wei-Hua Wu; Bo-Shiun Chen
Journal:  J Biol Chem       Date:  2015-07-30       Impact factor: 5.157

10.  NMDA receptor-dependent regulation of axonal and dendritic branching.

Authors:  Li-Jen Lee; Fu-Sun Lo; Reha S Erzurumlu
Journal:  J Neurosci       Date:  2005-03-02       Impact factor: 6.167
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