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Literature DB >> 12539951

The KEGG database.

Abstract

KEGG (http://www.genome.ad.jp/kegg/) is a suite of databases and associated software for understanding and simulating higher-order functional behaviours of the cell or the organism from its genome information. First, KEGG computerizes data and knowledge on protein interaction networks (PATHWAY database) and chemical reactions (LIGAND database) that are responsible for various cellular processes. Second, KEGG attempts to reconstruct protein interaction networks for all organisms whose genomes are completely sequenced (GENES and SSDB databases). Third, KEGG can be utilized as reference knowledge for functional genomics (EXPRESSION database) and proteomics (BRITE database) experiments. I will review the current status of KEGG and report on new developments in graph representation and graph computations.

Mesh：

Substances：
Ligands
Proteome

Year: 2002 PMID： 12539951

Source DB: PubMed Journal: Novartis Found Symp ISSN： 1528-2511

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Cited

423 in total

1. Composite functional module inference: detecting cooperation between transcriptional regulation and protein interaction by mantel test.

Authors: Chao Wu; Fan Zhang; Xia Li; Shihua Zhang; Jiang Li; Fei Su; Kongning Li; Yuqing Yan
Journal: BMC Syst Biol Date: 2010-06-10

2. Nematode.net: a tool for navigating sequences from parasitic and free-living nematodes.

Authors: Todd Wylie; John C Martin; Michael Dante; Makedonka Dautova Mitreva; Sandra W Clifton; Asif Chinwalla; Robert H Waterston; Richard K Wilson; James P McCarter
Journal: Nucleic Acids Res Date: 2004-01-01 Impact factor: 16.971

3. Systems level insights into the stress response to UV radiation in the halophilic archaeon Halobacterium NRC-1.

Authors: Nitin S Baliga; Sarah J Bjork; Richard Bonneau; Min Pan; Chika Iloanusi; Molly C H Kottemann; Leroy Hood; Jocelyne DiRuggiero
Journal: Genome Res Date: 2004-05-12 Impact factor: 9.043

4. Taking the next step: building an Arabidopsis information portal.

Authors:
Journal: Plant Cell Date: 2012-06-29 Impact factor: 11.277

5. Insights into colon cancer etiology via a regularized approach to gene set analysis of GWAS data.

Authors: Lin S Chen; Carolyn M Hutter; John D Potter; Yan Liu; Ross L Prentice; Ulrike Peters; Li Hsu
Journal: Am J Hum Genet Date: 2010-06-11 Impact factor: 11.025

6. Intricate interplay between astrocytes and motor neurons in ALS.

Authors: Hemali P Phatnani; Paolo Guarnieri; Brad A Friedman; Monica A Carrasco; Michael Muratet; Sean O'Keeffe; Chiamaka Nwakeze; Florencia Pauli-Behn; Kimberly M Newberry; Sarah K Meadows; Juan Carlos Tapia; Richard M Myers; Tom Maniatis
Journal: Proc Natl Acad Sci U S A Date: 2013-02-06 Impact factor: 11.205

The KEGG database.

1. Composite functional module inference: detecting cooperation between transcriptional regulation and protein interaction by mantel test.

2. Nematode.net: a tool for navigating sequences from parasitic and free-living nematodes.

3. Systems level insights into the stress response to UV radiation in the halophilic archaeon Halobacterium NRC-1.

4. Taking the next step: building an Arabidopsis information portal.

5. Insights into colon cancer etiology via a regularized approach to gene set analysis of GWAS data.

6. Intricate interplay between astrocytes and motor neurons in ALS.

7. Histone acetylation maps in aged mice developmentally exposed to lead: epigenetic drift and Alzheimer-related genes.

8. Effects of Zhizi Chuanxiong Capsule () on the Abnormal Methylation in Rabbits with Atherosclerosis.

9. Pathway crosstalk analysis of microarray gene expression profile in human hepatocellular carcinoma.

10. Identification of targeted analyte clusters for studies of schizophrenia.