| Literature DB >> 1253898 |
Abstract
The influence of inhibition or stimulation of cellular DNA synthesis on tick-borne virus antigen production in persistently infected cell culture was studied. Either mitomycin C or cytosine-arabinoside caused cessation of antigen-containing cell number increase. Stimulation of cellular DNA synthesis by growth medium change increased the level of antigen-containing cells. When HEp-2-Sof culture was synchronized, a correlation was observed between the entrance of cells into DNA synthesis phase and the increase of proportion of antigen-containing cells.Entities:
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Year: 1976 PMID: 1253898 DOI: 10.1007/BF01940816
Source DB: PubMed Journal: Experientia ISSN: 0014-4754