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Literature DB >> 1253890

A possible chemical basis for the higher mutagenicity of marijuana smoke as compared to tobacco smoke.

Abstract

The results of comparative anslyses of polynuclear aromatic hydrocarbons in marijuana and tobacco smoke indicate a considerably higher content of potential carcinogens in the former. A model experiment involving delta9-tetrahydrocannabinol suggests that the pyrolysis products of cannabinoids are major contributors to the polynuclear aromatic hydrocarbons.

Entities: Chemical Species

Mesh：

Substances：
Mutagens
Smoke
Dronabinol

Year: 1976 PMID： 1253890 DOI： 10.1007/BF01940790

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

9 in total

1. Marihuana: the grass may no longer be greener.

Authors: T H Maugh
Journal: Science Date: 1974-08-23 Impact factor: 47.728

2. [Contribution on the carcinogenic effect of dibenzopyrenes].

Authors: D Hoffmann; E L Wynder
Journal: Z Krebsforsch Date: 1966

3. Carcinogenicity of different polycyclic hydrocarbons in the respiratory tract of hamsters.

Authors: A Sellakumar; P Shubik
Journal: J Natl Cancer Inst Date: 1974-12 Impact factor: 13.506

4. The methods for fractionation, analytical separation and identification of polynuclear aromatic hydrocarbons in complex mixtures.

Authors: M Novotny; M L Lee; K D Bartle
Journal: J Chromatogr Sci Date: 1974-10 Impact factor: 1.618

5. Chemical studies on tobacco smoke. XXII. On the profile analysis of tobacco smoke.

Authors: D Hoffmann; G Rathkamp; K D Brunnemann; E L Wynder
Journal: Sci Total Environ Date: 1973-11 Impact factor: 7.963

6. Effects of marijuana and tobacco smoke on human lung physiology.

Authors: C Leuchtenberger; R Leuchtenberger; A Schneider
Journal: Nature Date: 1973-01-12 Impact factor: 49.962

7. Effects of marijuana and tobacco smoke on DNA and chromosomal complement in human lung explants.

Authors: C Leuchtenberger; R Leuchtenberger; U Ritter; N Inui
Journal: Nature Date: 1973-04-06 Impact factor: 49.962

8. The cannabinoid content of Cannabis sativa L grown in England.

Authors: J W Fairbairn; J A Liebmann
Journal: J Pharm Pharmacol Date: 1974-06 Impact factor: 3.765

9. Morphological and cytochemical effects of marijuana cigarette smoke on epithelioid cells of lung explants from mice.

Authors: C Leuchtenberger; R Leuchtenberger
Journal: Nature Date: 1971-11-26 Impact factor: 49.962