S Moritz1, T S Woodward, C C Ruff. 1. Universitätsklinikum Hamburg-Eppendorf, Klinik für Psychiatrie und Psychotherapie, Hamburg, Germany.
Abstract
BACKGROUND: The present study attempted to extend previous research on source monitoring deficits in schizophrenia. We hypothesized that patients would show a bias to attribute self-generated words to an external source. Furthermore, it was expected that schizophrenic patients would be overconfident regarding false memory attributions. METHOD: Thirty schizophrenic and 21 healthy participants were instructed to provide a semantic association for 20 words. Subsequently, a list was read containing experimenter- and self-generated words as well as new words. The subject was required to identify each item as old/new, name the source. and state the degree of confidence for the source attribution. RESULTS: Schizophrenic patients displayed a significantly increased number of source attribution errors and were significantly more confident than controls that a false source attribution response was true. The latter bias was ameliorated by higher doses of neuroleptics. CONCLUSIONS: It is inferred that a core cognitive deficit underlying schizophrenia is a failure to distinguish false from true mnestic contents.
BACKGROUND: The present study attempted to extend previous research on source monitoring deficits in schizophrenia. We hypothesized that patients would show a bias to attribute self-generated words to an external source. Furthermore, it was expected that schizophrenicpatients would be overconfident regarding false memory attributions. METHOD: Thirty schizophrenic and 21 healthy participants were instructed to provide a semantic association for 20 words. Subsequently, a list was read containing experimenter- and self-generated words as well as new words. The subject was required to identify each item as old/new, name the source. and state the degree of confidence for the source attribution. RESULTS:Schizophrenicpatients displayed a significantly increased number of source attribution errors and were significantly more confident than controls that a false source attribution response was true. The latter bias was ameliorated by higher doses of neuroleptics. CONCLUSIONS: It is inferred that a core cognitive deficit underlying schizophrenia is a failure to distinguish false from true mnestic contents.
Authors: J Daniel Ragland; Erin McCarthy; Warren B Bilker; Colleen M Brensinger; Jeffrey Valdez; Christian Kohler; Raquel E Gur; Ruben C Gur Journal: Psychol Med Date: 2006-05 Impact factor: 7.723