Literature DB >> 12536501

[PLA2 activity in serum and cutaneous tissues in patients with psoriasis vulgaris].

G Y Zhang1, Y C Zhang, Q L Zhang.   

Abstract

We examined the activity of PLA2 by quick simple trace titration method in the serum and cutaneous tissues in patients with psoriasis vulgaris patients than that in the control group. The activity of PLA2 was significantly higher in psoriasis vulgaris patients than that in the control group. PLA2 activity in sera of psoriasis patients in the active stage or rash area > 30% was higher than that in the inactive stage or rash area < 30%. It is suggested that the sera PLA2 activity may be related to the disease activity in patients with psoriasis vulgaris, and PLA2 may play an important role in the pathogenesis of the psoriasis.

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Year:  2001        PMID: 12536501

Source DB:  PubMed          Journal:  Hunan Yi Ke Da Xue Xue Bao        ISSN: 1000-5625


  2 in total

1.  Phospholipase A2 enzymes represent a shared pathogenic pathway in psoriasis and pityriasis rubra pilaris.

Authors:  Shuai Shao; Jiaoling Chen; William R Swindell; Lam C Tsoi; Xianying Xing; Feiyang Ma; Ranjitha Uppala; Mrinal K Sarkar; Olesya Plazyo; Allison C Billi; Rachael Wasikowski; Kathleen M Smith; Prisca Honore; Victoria E Scott; Emanual Maverakis; J Michelle Kahlenberg; Gang Wang; Nicole L Ward; Paul W Harms; Johann E Gudjonsson
Journal:  JCI Insight       Date:  2021-10-22

2.  Inhibition of phospholipases suppresses progression of psoriasis through modulation of inflammation.

Authors:  Yunlu Gao; Jiajing Lu; Xunxia Bao; Xuemei Yi; Chen Peng; Wenjuan Chen; Timing Zhen; Yong Shi; Kaichen Xing; Sibo Zhu; Yangfeng Ding
Journal:  Exp Biol Med (Maywood)       Date:  2021-02-27
  2 in total

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