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Literature DB >> 12536325

Developmental expression of the Xenopus laevis Tbx20 orthologue.

Daniel DeWitt Brown¹, Olav Binder, Maria Pagratis, Brian A Parr, Frank L Conlon.

Abstract

We have isolated the Xenopus orthologue of the T-box gene, Tbx20, and characterized its developmental expression profile. We show that Tbx20 is one of the earliest markers of heart tissue in Xenopus, and is expressed throughout all cardiac tissue during later stages of development. In addition, we also observe expression in the cement gland, the jugular vein, the lung bud, the cloacal aperture, rhombomeres 2, 4, 6 and 8, and in a subset of motor neurons.

Entities: Gene Species

Mesh：

Substances：
T-Box Domain Proteins

Year: 2002 PMID： 12536325 PMCID： PMC1635808 DOI： 10.1007/s00427-002-0276-6

Source DB: PubMed Journal: Dev Genes Evol ISSN： 0949-944X Impact factor: 0.900

19 in total

1. Tbx12, a novel T-box gene, is expressed during early stages of heart and retinal development.

Authors: C T Carson; E R Kinzler; B A Parr
Journal: Mech Dev Date: 2000-08 Impact factor: 1.882

2. tbx20, a new vertebrate T-box gene expressed in the cranial motor neurons and developing cardiovascular structures in zebrafish.

Authors: D G Ahn; I Ruvinsky; A C Oates; L M Silver; R K Ho
Journal: Mech Dev Date: 2000-07 Impact factor: 1.882

Review 3. T-box genes in development: from hydra to humans.

Authors: V E Papaioannou
Journal: Int Rev Cytol Date: 2001

4. Characterization of the human TBX20 gene, a new member of the T-Box gene family closely related to the Drosophila H15 gene.

Authors: M Meins; D J Henderson; S S Bhattacharya; J C Sowden
Journal: Genomics Date: 2000-08-01 Impact factor: 5.736

5. DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1.

Authors: L A Jerome; V E Papaioannou
Journal: Nat Genet Date: 2001-03 Impact factor: 38.330

6. TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome.

Authors: S Merscher; B Funke; J A Epstein; J Heyer; A Puech; M M Lu; R J Xavier; M B Demay; R G Russell; S Factor; K Tokooya; B S Jore; M Lopez; R K Pandita; M Lia; D Carrion; H Xu; H Schorle; J B Kobler; P Scambler; A Wynshaw-Boris; A I Skoultchi; B E Morrow; R Kucherlapati
Journal: Cell Date: 2001-02-23 Impact factor: 41.582

7. Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice.

Authors: E A Lindsay; F Vitelli; H Su; M Morishima; T Huynh; T Pramparo; V Jurecic; G Ogunrinu; H F Sutherland; P J Scambler; A Bradley; A Baldini
Journal: Nature Date: 2001-03-01 Impact factor: 49.962

8. Cloning and expression analysis of the mouse T-box gene tbx20.

Authors: F Kraus; B Haenig; A Kispert
Journal: Mech Dev Date: 2001-01 Impact factor: 1.882

9. Expression pattern of novel chick T-box gene, Tbx20.

Authors: A Iio; M Koide; K Hidaka; T Morisaki
Journal: Dev Genes Evol Date: 2001-10-19 Impact factor: 0.900

Review 10. The T-box family.

Authors: Val Wilson; Frank L Conlon
Journal: Genome Biol Date: 2002-05-31 Impact factor: 13.583

22 in total

Developmental expression of the Xenopus laevis Tbx20 orthologue.

1. Tbx12, a novel T-box gene, is expressed during early stages of heart and retinal development.

2. tbx20, a new vertebrate T-box gene expressed in the cranial motor neurons and developing cardiovascular structures in zebrafish.

Review 3. T-box genes in development: from hydra to humans.

4. Characterization of the human TBX20 gene, a new member of the T-Box gene family closely related to the Drosophila H15 gene.

5. DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1.

6. TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome.

7. Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice.

8. Cloning and expression analysis of the mouse T-box gene tbx20.

9. Expression pattern of novel chick T-box gene, Tbx20.

Review 10. The T-box family.

1. A Gro/TLE-NuRD corepressor complex facilitates Tbx20-dependent transcriptional repression.

2. Tbx20 regulation of endocardial cushion cell proliferation and extracellular matrix gene expression.

3. Small heat shock protein Hsp27 is required for proper heart tube formation.

Review 4. Cardiac progenitors and the embryonic cell cycle.

5. SHP-2 is required for the maintenance of cardiac progenitors.

6. Cardiac neural crest is dispensable for outflow tract septation in Xenopus.

7. Dual developmental role of transcriptional regulator Ets1 in Xenopus cardiac neural crest vs. heart mesoderm.

8. Association of TBX20 gene polymorphism with congenital heart disease in Han Chinese neonates.

9. Tbx20 drives cardiac progenitor formation and cardiomyocyte proliferation in zebrafish.

10. Congenital heart disease protein 5 associates with CASZ1 to maintain myocardial tissue integrity.