Literature DB >> 12535513

Dissecting various ATP-dependent steps involved in proteasomal degradation.

Teru Ogura1, Keiji Tanaka.   

Abstract

Proteolysis by archaeal 20S proteasomes and the PAN (proteasome-activating nucleotidase) regulatory complex, a homolog of the eukaryotic 19S AAA ATPases, requires ATP hydrolysis through multiple steps. ATP hydrolysis, activated by binding of substrates to PAN, is utilized for substrate unfolding, gate opening of 20S proteasomes, and substrate translocation.

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Year:  2003        PMID： 12535513     DOI： 10.1016/s1097-2765(03)00004-2

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  6 in total

1.  ATP binding and ATP hydrolysis play distinct roles in the function of 26S proteasome.

Authors:  Chang-Wei Liu; Xiaohua Li; David Thompson; Kerry Wooding; Tsui-ling Chang; Zhanyun Tang; Hongtao Yu; Philip J Thomas; George N DeMartino
Journal:  Mol Cell       Date:  2006-10-06       Impact factor: 17.970

2.  Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entry.

Authors:  David M Smith; Shih-Chung Chang; Soyeon Park; Daniel Finley; Yifan Cheng; Alfred L Goldberg
Journal:  Mol Cell       Date:  2007-09-07       Impact factor: 17.970

3.  Investigation on the 19S ATPase proteasome subunits (Rpt1-6) conservation and their differential gene expression in Schistosoma mansoni.

Authors:  Olavo S Pereira-Júnior; Roberta Verciano Pereira; Camila S Silva; William Castro-Borges; Renata Guerra Sá; Fernanda J Cabral; Sérgio H Silva; Cláudia S Soares; Enyara R Morais; Erika B C Moreira; Lizandra G Magalhães; Fabiana M de Paula; Vanderlei Rodrigues
Journal:  Parasitol Res       Date:  2012-09-28       Impact factor: 2.289

4.  Early Forms of α-Synuclein Pathology Are Associated with Neuronal Complex I Deficiency in the Substantia Nigra of Individuals with Parkinson's Disease.

Authors:  Irene Hana Flønes; Harald Nyland; Dagny-Ann Sandnes; Guido Werner Alves; Ole-Bjørn Tysnes; Charalampos Tzoulis
Journal:  Biomolecules       Date:  2022-05-25

5.  Direct ubiquitin independent recognition and degradation of a folded protein by the eukaryotic proteasomes-origin of intrinsic degradation signals.

Authors:  Amit Kumar Singh Gautam; Satish Balakrishnan; Prasanna Venkatraman
Journal:  PLoS One       Date:  2012-04-10       Impact factor: 3.240

6.  MFN2 mediates ER-mitochondrial coupling during ER stress through specialized stable contact sites.

Authors:  Benjamin Gottschalk; Zhanat Koshenov; Olaf A Bachkoenig; René Rost; Roland Malli; Wolfgang F Graier
Journal:  Front Cell Dev Biol       Date:  2022-09-08
  6 in total

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