L Say1, A M Gülmezoglu, G J Hofmeyr. 1. Department of Reproductive Health and Research, World Health Organization, 20 Avenue Appia, Geneva 27, Switzerland. sayl@who.int
Abstract
BACKGROUND: It has been suggested that oestrogens may improve fetal growth due to an increase in nutritional supply to the fetus from greater uterine blood flow. OBJECTIVES: The objective of this review was to assess the effects of hormone administration for suspected impaired fetal growth and perinatal outcome. SEARCH STRATEGY: We searched the Cochrane Pregnancy and Childbirth Group trials register (1 November 2002). SELECTION CRITERIA: Acceptably controlled trials of hormone administration for suspected impaired fetal growth which report fetal, perinatal or maternal outcomes. DATA COLLECTION AND ANALYSIS: Eligibility and trial quality were assessed. MAIN RESULTS: No studies were included since none of the potentially relevant trials reported clinical outcomes. REVIEWER'S CONCLUSIONS: There is not enough evidence to evaluate the clinical use of hormone administration for suspected impaired fetal growth.
BACKGROUND: It has been suggested that oestrogens may improve fetal growth due to an increase in nutritional supply to the fetus from greater uterine blood flow. OBJECTIVES: The objective of this review was to assess the effects of hormone administration for suspected impaired fetal growth and perinatal outcome. SEARCH STRATEGY: We searched the Cochrane Pregnancy and Childbirth Group trials register (1 November 2002). SELECTION CRITERIA: Acceptably controlled trials of hormone administration for suspected impaired fetal growth which report fetal, perinatal or maternal outcomes. DATA COLLECTION AND ANALYSIS: Eligibility and trial quality were assessed. MAIN RESULTS: No studies were included since none of the potentially relevant trials reported clinical outcomes. REVIEWER'S CONCLUSIONS: There is not enough evidence to evaluate the clinical use of hormone administration for suspected impaired fetal growth.