OBJECTIVES: To estimate the prevalence of myocardial damage in falciparum malaria by serum concentration of cardiac troponin T. METHODS: Retrospective study of stored sera and patient files; assessment of acute myocardial damage by serum concentration or activity of cardiac troponin T, creatine kinase, creatine kinase MB and myoglobin and by routine electrocardiography. RESULTS: A total of 161 patients with falciparum malaria were included in the study; troponin T was elevated in one case (0.6%), no CK-MB elevations were found, myoglobin was elevated in 10 of 161 patients (6.2%), all of whom were elderly and had concomitant elevated serum concentration levels of cystatin C; ECG abnormalities were seen in 23 patients. CONCLUSION: Assessed by troponin T, myocardial damage in falciparum malaria is rare.
OBJECTIVES: To estimate the prevalence of myocardial damage in falciparum malaria by serum concentration of cardiac troponin T. METHODS: Retrospective study of stored sera and patient files; assessment of acute myocardial damage by serum concentration or activity of cardiac troponin T, creatine kinase, creatine kinase MB and myoglobin and by routine electrocardiography. RESULTS: A total of 161 patients with falciparum malaria were included in the study; troponin T was elevated in one case (0.6%), no CK-MB elevations were found, myoglobin was elevated in 10 of 161 patients (6.2%), all of whom were elderly and had concomitant elevated serum concentration levels of cystatin C; ECG abnormalities were seen in 23 patients. CONCLUSION: Assessed by troponin T, myocardial damage in falciparum malaria is rare.
Authors: Louise Roggelin; Daniel Pelletier; Josephine N Hill; Torsten Feldt; Steffi Hoffmann; Daniel Ansong; Justice Sylverken; Jürgen Burhenne; Johanna Fischer-Herr; Parisa Mehrfar; Christian Thiel; Gerd D Burchard; Samuel B Nguah; Jakob P Cramer Journal: Malar J Date: 2014-06-05 Impact factor: 2.979
Authors: An-Emmie Nieman; Quirijn de Mast; Meta Roestenberg; Jorien Wiersma; Gheorghe Pop; Anton Stalenhoef; Pierre Druilhe; Robert Sauerwein; André van der Ven Journal: Malar J Date: 2009-12-03 Impact factor: 2.979
Authors: Yuri C Martins; Leah Clemmer; Pamela Orjuela-Sánchez; Graziela M Zanini; Peng Kai Ong; John A Frangos; Leonardo J M Carvalho Journal: Malar J Date: 2013-04-24 Impact factor: 2.979
Authors: Maurits P A van Meer; Guido J H Bastiaens; Mohamed Boulaksil; Quirijn de Mast; Anusha Gunasekera; Stephen L Hoffman; Gheorghe Pop; André J A M van der Ven; Robert W Sauerwein Journal: Malar J Date: 2014-01-30 Impact factor: 2.979