| Literature DB >> 12535003 |
C Pozzilli1, V Tomassini, F Marinelli, A Paolillo, C Gasperini, S Bastianello.
Abstract
The authors evaluated the gender difference in the magnetic resonance imaging characteristics of the lesions occurring in the brain of 413 multiple sclerosis (MS) patients. Men had fewer contrast-enhancing lesions (P = 0.01), but a higher proportion of lesions evolving into 'black holes' (P = 0.001), when compared with women. Thus, our data indicate that men with MS are prone to develop less inflammatory, but more destructive lesions than women. This study results provides support for a modulation of the MS pathological changes by gender.Entities:
Mesh：
Year: 2003 PMID： 12535003 DOI： 10.1046/j.1468-1331.2003.00519.x
Source DB: PubMed Journal: Eur J Neurol ISSN： 1351-5101 Impact factor: 6.089