| Literature DB >> 12531931 |
Martin J Hug1, Tsutomu Tamada, Robert J Bridges.
Abstract
Defective HCO(3)(-) and fluid secretion are hallmarks of the pathophysiology of the pancreas of cystic fibrosis patients. Recently, impaired HCO(3)(-) secretion has been shown in most tissues known to express the cystic fibrosis transmembrane conductance regulator (CFTR). New results suggest that CFTR plays an important role in the transcellular secretion of HCO(3)(-).Entities:
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Year: 2003 PMID: 12531931 DOI: 10.1152/nips.01412.2002
Source DB: PubMed Journal: News Physiol Sci ISSN: 0886-1714