Literature DB >> 12531929

Ubiquitin-dependent proteolysis in neurons.

Lars Klimaschewski1.   

Abstract

Various studies identified the ubiquitin-proteasome system as the prime suspect in causing neurodegenerative diseases. The present review summarizes our current knowledge about the expression, regulation, and functions of this major protein degradation pathway in the brain, with particular reference to the pathogenesis of associated neurological diseases.

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Year:  2003        PMID： 12531929     DOI： 10.1152/nips.01408.2002

Source DB:  PubMed          Journal:  News Physiol Sci        ISSN： 0886-1714


  5 in total

Review 1.  Post-translational regulation of neuronal nitric oxide synthase: implications for sympathoexcitatory states.

Authors:  Neeru M Sharma; Kaushik P Patel
Journal:  Expert Opin Ther Targets       Date:  2016-12-02       Impact factor: 6.902

2.  Cowden syndrome-related mutations in PTEN associate with enhanced proteasome activity.

Authors:  Xin He; Nicholas Arrotta; Deepa Radhakrishnan; Yu Wang; Todd Romigh; Charis Eng
Journal:  Cancer Res       Date:  2013-03-08       Impact factor: 12.701

3.  Brain aging in acquired immunodeficiency syndrome: increased ubiquitin-protein conjugate is correlated with decreased synaptic protein but not amyloid plaque accumulation.

Authors:  Benjamin B Gelman; Kimberly Schuenke
Journal:  J Neurovirol       Date:  2004-04       Impact factor: 2.643

4.  The Impact of MicroRNAs on Brain Aging and Neurodegeneration.

Authors:  Stephan P Persengiev; Ivanela I Kondova; Ronald E Bontrop
Journal:  Curr Gerontol Geriatr Res       Date:  2012-01-18

5.  Functional Annotation of Small Noncoding RNAs Target Genes Provides Evidence for a Deregulated Ubiquitin-Proteasome Pathway in Spinocerebellar Ataxia Type 1.

Authors:  Stephan Persengiev; Ivanela Kondova; Ronald E Bontrop
Journal:  J Nucleic Acids       Date:  2012-10-03
  5 in total

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