Literature DB >> 12531927

Small G proteins as novel therapeutic targets in cardiovascular medicine.

Christine Barandier1, Xiu-Fen Ming, Zhihong Yang.   

Abstract

Small G proteins are implicated in regulation of endothelial function, smooth muscle cell contraction, proliferation, and migration, as well as cardiomyocyte hypertrophy. Targeting small G proteins and their downstream signaling could constitute promising therapeutic approaches in cardiovascular disorders such as atherosclerosis, restenosis, hypertension, vasospasm, and cardiac hypertrophy.

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Year:  2003        PMID： 12531927     DOI： 10.1152/nips.01407.2002

Source DB:  PubMed          Journal:  News Physiol Sci        ISSN： 0886-1714


  3 in total

1.  The role of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors (statins) in modern rheumatology.

Authors:  Przemyslaw Kotyla
Journal:  Ther Adv Musculoskelet Dis       Date:  2010-10       Impact factor: 5.346

2.  Cell-volume-dependent vascular smooth muscle contraction: role of Na+, K+, 2Cl- cotransport, intracellular Cl- and L-type Ca2+ channels.

Authors:  Yana J Anfinogenova; Mikhail B Baskakov; Igor V Kovalev; Alexander A Kilin; Nickolai O Dulin; Sergei N Orlov
Journal:  Pflugers Arch       Date:  2004-10       Impact factor: 3.657

3.  Therapeutic effects of astragaloside IV on myocardial injuries: multi-target identification and network analysis.

Authors:  Jing Zhao; Pengyuan Yang; Fan Li; Lin Tao; Hong Ding; Yaocheng Rui; Zhiwei Cao; Weidong Zhang
Journal:  PLoS One       Date:  2012-09-17       Impact factor: 3.240
  3 in total

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