Literature DB >> 12531540

Roles of phospholipase D in apoptosis and pro-survival.

Yoshinori Nozawa1.   

Abstract

Accumulating evidence has recognized phospholipase D (PLD) as an important element in signal transduction of cell responses, including proliferation and differentiation, However, its role in pro-apoptotic, anti-apoptotic or pro-survival signaling is not well-understood. Involvement of PLD in these signaling mechanisms is considered to differ depending on the cell type and the extracellular stimulus.

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Year:  2002        PMID： 12531540     DOI： 10.1016/s1388-1981(02)00327-x

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  12 in total

1.  Shear stress induces cell apoptosis via a c-Src-phospholipase D-mTOR signaling pathway in cultured podocytes.

Authors:  Chunfa Huang; Leslie A Bruggeman; Lindsey M Hydo; R Tyler Miller
Journal:  Exp Cell Res       Date:  2012-03-26       Impact factor: 3.905

2.  Requirement of phospholipase D1 activity in H-RasV12-induced transformation.

Authors:  F Gregory Buchanan; Matt McReynolds; Anthony Couvillon; Yoonseok Kam; Vijaykumar R Holla; Raymond N Dubois; John H Exton
Journal:  Proc Natl Acad Sci U S A       Date:  2005-01-24       Impact factor: 11.205

3.  Effect of tricyclodecan-9-yl potassium xanthate (D609) on phospholipid metabolism and cell death during oxygen-glucose deprivation in PC12 cells.

Authors:  E C Larsen; J F Hatcher; R M Adibhatla
Journal:  Neuroscience       Date:  2007-04-16       Impact factor: 3.590

4.  Coexistence of phosphatidylcholine-specific phospholipase C and phospholipase D activities in rat cerebral cortex synaptosomes.

Authors:  Melina V Mateos; Romina M Uranga; Gabriela A Salvador; Norma M Giusto
Journal:  Lipids       Date:  2006-03       Impact factor: 1.880

Review 5.  Targeting phospholipase D with small-molecule inhibitors as a potential therapeutic approach for cancer metastasis.

Authors:  Wenjuan Su; Qin Chen; Michael A Frohman
Journal:  Future Oncol       Date:  2009-11       Impact factor: 3.404

6.  Phospholipase D elevates the level of MDM2 and suppresses DNA damage-induced increases in p53.

Authors:  Li Hui; Tarek Abbas; Rafal M Pielak; Troy Joseph; Jill Bargonetti; David A Foster
Journal:  Mol Cell Biol       Date:  2004-07       Impact factor: 4.272

7.  Mutation of Y179 on phospholipase D2 (PLD2) upregulates DNA synthesis in a PI3K-and Akt-dependent manner.

Authors:  Mauricio Di Fulvio; Kathleen Frondorf; Julian Gomez-Cambronero
Journal:  Cell Signal       Date:  2007-10-13       Impact factor: 4.315

8.  The triangle of death of neurons: Oxidative damage, mitochondrial dysfunction, and loss of choline-containing biomolecules in brains of mice treated with doxorubicin. Advanced insights into mechanisms of chemotherapy induced cognitive impairment ("chemobrain") involving TNF-α.

Authors:  Xiaojia Ren; Jeriel T R Keeney; Sumitra Miriyala; Teresa Noel; David K Powell; Luksana Chaiswing; Subbarao Bondada; Daret K St Clair; D Allan Butterfield
Journal:  Free Radic Biol Med       Date:  2018-12-26       Impact factor: 7.376

9.  Overexpression of phospholipase D prevents actinomycin D-induced apoptosis through potentiation of phosphoinositide 3-kinase signalling pathways in Chinese-hamster ovary cells.

Authors:  Momoko Yamada; Yoshiko Banno; Yoh Takuwa; Masahiro Koda; Akira Hara; Yoshinori Nozawa
Journal:  Biochem J       Date:  2004-03-01       Impact factor: 3.857

10.  Arbutin and decrease of potentially toxic substances generated in human blood neutrophils.

Authors:  Jana Pečivová; Radomír Nosál'; Klára Sviteková; Tatiana Mačičková
Journal:  Interdiscip Toxicol       Date:  2015-03-04
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