Literature DB >> 1252940

The periaqueductal gray: site of morphine analgesia and tolerance as shown by 2-way cross tolerance between systemic and intracerebral injections.

Y F Jacquet, A Lajtha.   

Abstract

The periaqueductal gray was shown to be an important component of morphine analgesia and tolerance. Two-way analgesic cross tolerance was obtained between systemic and intracerebral morphine administrations when the intracerebral site was the periaqueductal gray. Rats were pretreated with intraperitoneal morphine and tested with intracerebral morphine in the periaqueductal gray. A dose-dependent reduction in analgesia as a function of morphine pretreatment level was obtained. Conversely, when rats were pretreated with intracerebral morphine in the periaqueductal gray and tested with intraperitoneal morphine, significant reductions in analgesia were obtained.

Entities:  

Mesh：

Substances：

Year:  1976        PMID： 1252940     DOI： 10.1016/0006-8993(76)90448-0

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  31 in total

1.  Morphine drives internal ribosome entry site-mediated hnRNP K translation in neurons through opioid receptor-dependent signaling.

Authors:  Pin-Tse Lee; Po-Kuan Chao; Li-Chin Ou; Jian-Ying Chuang; Yen-Chang Lin; Shu-Chun Chen; Hsiao-Fu Chang; Ping-Yee Law; Horace H Loh; Yu-Sheng Chao; Tsung-Ping Su; Shiu-Hwa Yeh
Journal:  Nucleic Acids Res       Date:  2014-10-31       Impact factor: 16.971

2.  Opiate and stimulus-produced analgesia: functional anatomy of a medullospinal pathway.

Authors:  A I Basbaum; C H Clanton; H L Fields
Journal:  Proc Natl Acad Sci U S A       Date:  1976-12       Impact factor: 11.205

3.  Attenuation of the morphine withdrawal syndrome by inhibition of catabolism of endogenous enkephalins in the periaqueductal gray matter.

Authors:  R Maldonado; M C Fournié-Zaluski; B P Roques
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1992-04       Impact factor: 3.000

4.  Extracellular signal-regulated kinase 1/2 activation counteracts morphine tolerance in the periaqueductal gray of the rat.

Authors:  Tara A Macey; Erin N Bobeck; Deborah M Hegarty; Sue A Aicher; Susan L Ingram; Michael M Morgan
Journal:  J Pharmacol Exp Ther       Date:  2009-08-14       Impact factor: 4.030

5.  micro-Opioid receptor stimulation in the medial subnucleus of the tractus solitarius inhibits gastric tone and motility by reducing local GABA activity.

Authors:  Melissa A Herman; Alisa Alayan; Niaz Sahibzada; Barbara Bayer; Joseph Verbalis; Kenneth L Dretchen; Richard A Gillis
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2010-05-20       Impact factor: 4.052

Review 6.  Inflammatory mediators of opioid tolerance: Implications for dependency and addiction.

Authors:  Lori N Eidson; Anne Z Murphy
Journal:  Peptides       Date:  2019-03-16       Impact factor: 3.750

7.  Reduction of morphine dependence and potentiation of analgesia by chronic co-administration of nifedipine.

Authors:  L Antkiewicz-Michaluk; J Michaluk; I Romańska; J Vetulani
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

8.  Relative contribution of the dorsal raphe nucleus and ventrolateral periaqueductal gray to morphine antinociception and tolerance in the rat.

Authors:  Kyle N Campion; Kimber A Saville; Michael M Morgan
Journal:  Eur J Neurosci       Date:  2016-09-14       Impact factor: 3.386

9.  Differential desensitization of mu- and delta- opioid receptors in selected neural pathways following chronic morphine treatment.

Authors:  F Noble; B M Cox
Journal:  Br J Pharmacol       Date:  1996-01       Impact factor: 8.739

10.  Stimulus-evoked release of tritiated monoamines from rat periaqueductal gray slices in vitro and its receptor-mediated modulation.

Authors:  D H Versteeg; T Csikós; H Spierenburg
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1991-06       Impact factor: 3.000
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.