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Literature DB >> 12528988

New multidrug resistance reversal agents.

Abstract

Multidrug resistance (MDR) to antitumor agents represents a significant challenge to effective chemotherapy. The use of MDR modulators is a promising approach to overcome the undesired MDR phenotype. The more effective MDR modulators are urgently needed for clinical use. This review focuses on literatures published in 1998-2001.

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Year: 2003 PMID： 12528988 DOI： 10.2174/1389450033347064

Source DB: PubMed Journal: Curr Drug Targets ISSN： 1389-4501 Impact factor: 3.465

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Cited

10 in total

1. Antitumor agents. 280. Multidrug resistance-selective desmosdumotin B analogues.

Authors: Kyoko Nakagawa-Goto; Po-Cheng Chang; Chin-Yu Lai; Hsin-Yi Hung; Tzu-Hsuan Chen; Pei-Chi Wu; Hao Zhu; Alexander Sedykh; Kenneth F Bastow; Kuo-Hsiung Lee
Journal: J Med Chem Date: 2010-09-23 Impact factor: 7.446

2. Antitumor Agents 291 Expanded B-Ring Modification Study of 6,8,8-Triethyl Desmosdumotin B Analogues as Multidrug-Resistance Selective Agents.

Authors: Kyoko Nakagawa-Goto; Kenneth F Bastow; Emika Ohkoshi; Susan L Morris-Natschke; Kuo-Hsiung Lee
Journal: Med Chem (Los Angeles) Date: 2011-12-01

Review 3. Multiple drug resistance mechanisms in cancer.

Authors: Bruce C Baguley
Journal: Mol Biotechnol Date: 2010-11 Impact factor: 2.695

4. Synthesis and anti-breast cancer activities of substituted quinolines.

Authors: Aibin Shi; Thu A Nguyen; Srinivas K Battina; Sandeep Rana; Dolores J Takemoto; Peter K Chiang; Duy H Hua
Journal: Bioorg Med Chem Lett Date: 2008-04-13 Impact factor: 2.823

Review 5. The anti-inflammatory non-antibiotic helper compound diclofenac: an antibacterial drug target.

Authors: K Mazumdar; S G Dastidar; J H Park; N K Dutta
Journal: Eur J Clin Microbiol Infect Dis Date: 2009-04-28 Impact factor: 3.267

6. 3,5-Dibenzoyl-4-(3-phenoxyphenyl)-1,4-dihydro-2,6-dimethylpyridine (DP7) as a new multidrug resistance reverting agent devoid of effects on vascular smooth muscle contractility.

Authors: Simona Saponara; Masami Kawase; Anamik Shah; Noboru Motohashi; Joseph Molnar; Katalin Ugocsai; Giampietro Sgaragli; Fabio Fusi
Journal: Br J Pharmacol Date: 2004-01-12 Impact factor: 8.739

New multidrug resistance reversal agents.

1. Antitumor agents. 280. Multidrug resistance-selective desmosdumotin B analogues.

2. Antitumor Agents 291 Expanded B-Ring Modification Study of 6,8,8-Triethyl Desmosdumotin B Analogues as Multidrug-Resistance Selective Agents.

Review 3. Multiple drug resistance mechanisms in cancer.

4. Synthesis and anti-breast cancer activities of substituted quinolines.

Review 5. The anti-inflammatory non-antibiotic helper compound diclofenac: an antibacterial drug target.

6. 3,5-Dibenzoyl-4-(3-phenoxyphenyl)-1,4-dihydro-2,6-dimethylpyridine (DP7) as a new multidrug resistance reverting agent devoid of effects on vascular smooth muscle contractility.

7. The effect of the PQ1 anti-breast cancer agent on normal tissues.

8. Cytotoxic effect of some 1, 4-dihydropyridine derivatives containing nitroimidazole moiety.

9. Modification of marine natural product ningalin B and SAR study lead to potent P-glycoprotein inhibitors.

10. miR-145 sensitizes breast cancer to doxorubicin by targeting multidrug resistance-associated protein-1.