Literature DB >> 12528727

Ultrastructural changes in osteocytes in microgravity conditions.

N V Rodionova1, V S Oganov, N V Zolotova.   

Abstract

We examined the histology and morphometry of biosamples (biopsies) of the iliac crest of monkeys, flown 14 days aboard the "Bion-11", using electron microscopy. We found, that some young osteocytes take part in the activation of collagen protein biosynthesis in the adaptive remodeling process of the bone tissue to microgravity conditions. Osteocyte lacunae filled with collagen fibrils; this correlates with fibrotic osteoblast reorganization in such zones. The osteolytic activity in mature osteocytes is intensified. As a result of osteocyte destruction, the quantity of empty osteocytic lacunae in the bone tissue increases. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

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Year:  2002        PMID： 12528727     DOI： 10.1016/s0273-1177(02)00393-9

Source DB:  PubMed          Journal:  Adv Space Res        ISSN： 0273-1177            Impact factor:   2.152


  17 in total

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