J Huang1, M Cai, G Li, D Wei, Y Tan. 1. Department of Immunology, School of Basic Medical Sciences, WCUMS, Chengdu 610041, China.
Abstract
OBJECTIVE: To find out whether hepatocellular carcinoma (HCC) cells express HLA-I antigens. METHODS: LSAB assay of immunohistochemistry was used to detect six frozen HCC specimens. RESULTS: All the HCC cells have strong expression of HLA-I antigens. CONCLUSION: In view of these data on the expression of HLA-I antigens, the authors deem it practical to develop HCC CTL vaccine.
OBJECTIVE: To find out whether hepatocellular carcinoma (HCC) cells express HLA-I antigens. METHODS: LSAB assay of immunohistochemistry was used to detect six frozen HCC specimens. RESULTS: All the HCC cells have strong expression of HLA-I antigens. CONCLUSION: In view of these data on the expression of HLA-I antigens, the authors deem it practical to develop HCC CTL vaccine.