Literature DB >> 12528313

NXY-059. Centaur.

Paul A Lapchak1.   

Abstract

Centaur and AstraZeneca are developing NXY-059, an alpha-phenyl-N-tert-butyl nitrone derivative, free radical trapping agent, for the potential therapy of reperfusion injury following stroke. Phase II clinical trials are ongoing, with phase III trials in acute stroke planned for initiation in early 2003.

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Year:  2002        PMID: 12528313

Source DB:  PubMed          Journal:  Curr Opin Investig Drugs        ISSN: 1472-4472


  3 in total

1.  CeeTox™ Analysis of CNB-001 a Novel Curcumin-Based Neurotrophic/Neuroprotective Lead Compound to Treat Stroke: Comparison with NXY-059 and Radicut.

Authors:  Paul A Lapchak; James M McKim
Journal:  Transl Stroke Res       Date:  2011-03       Impact factor: 6.829

2.  Translational stroke research using a rabbit embolic stroke model: a correlative analysis hypothesis for novel therapy development.

Authors:  Paul A Lapchak
Journal:  Transl Stroke Res       Date:  2010-04-02       Impact factor: 6.829

Review 3.  How is edaravone effective against acute ischemic stroke and amyotrophic lateral sclerosis?

Authors:  Kazutoshi Watanabe; Masahiko Tanaka; Satoshi Yuki; Manabu Hirai; Yorihiro Yamamoto
Journal:  J Clin Biochem Nutr       Date:  2017-11-11       Impact factor: 3.114

  3 in total

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