OBJECTIVE/ METHODS: The authors examined recurrence rates of major depression in elderly subjects with different foci of interpersonal psychotherapy (IPT), who were treated for up to 3 years with either monthlymaintenance IPT and pill placebo or with monthly clinical management and pill placebo. RESULTS: Among subjects with an IPT focus on role conflict, a greater proportion of those treated with maintenance-IPT survived for 3 years without recurrence than those treated with placebo/clinical management. Median time to recurrence was 68.9 weeks in IPT-treated patients versus 16.3 weeks for patients in clinical management. Subjects with an IPT focus on abnormal grief or role transition demonstrated no effect differential for maintenance IPT and pill-placebo on recurrence prevention over supportive clinical management and pill-placebo. CONCLUSION: If replicated in a larger sample, these findings have important implications for ongoing case-management decisions.
RCT Entities:
OBJECTIVE/ METHODS: The authors examined recurrence rates of major depression in elderly subjects with different foci of interpersonal psychotherapy (IPT), who were treated for up to 3 years with either monthly maintenance IPT and pill placebo or with monthly clinical management and pill placebo. RESULTS: Among subjects with an IPT focus on role conflict, a greater proportion of those treated with maintenance-IPT survived for 3 years without recurrence than those treated with placebo/clinical management. Median time to recurrence was 68.9 weeks in IPT-treated patients versus 16.3 weeks for patients in clinical management. Subjects with an IPT focus on abnormal grief or role transition demonstrated no effect differential for maintenance IPT and pill-placebo on recurrence prevention over supportive clinical management and pill-placebo. CONCLUSION: If replicated in a larger sample, these findings have important implications for ongoing case-management decisions.
Authors: Katrin E Harrison; Alexandre Y Dombrovski; Jennifer Q Morse; Patricia Houck; Maryann Schlernitzauer; Charles F Reynolds; Katalin Szanto Journal: Int Psychogeriatr Date: 2009-12-15 Impact factor: 3.878
Authors: Kristen Carreira; Mark D Miller; Ellen Frank; Patricia R Houck; Jennifer Q Morse; Mary Amanda Dew; Meryl A Butters'; Charles F Reynolds Journal: Int J Geriatr Psychiatry Date: 2008-11 Impact factor: 3.485