| Literature DB >> 12525903 |
Kiyomi Okamoto1, Naomasa Gotoh, Takeshi Nishino.
Abstract
Overproduction of multidrug efflux systems MexAB-OprM, MexCD-OprJ, and MexXY/OprM of Pseudomonas aeruginosa caused reduction of susceptibility of the mutant, which lacked AmpC and all three systems to panipenem, meropenem, S4661 and DU6681a; meropenem, S4661 and DU6681a; and BO2727, panipenem, meropenem, S4661 and DU6681a, respectively, but not reduction of the susceptibility to imipenem and biapenem. Thus, we determined substrate specificities of these efflux systems to carbapenems.Entities:
Mesh：
Substances：
Year: 2002 PMID： 12525903 DOI： 10.1007/s10156-002-0193-7
Source DB: PubMed Journal: J Infect Chemother ISSN： 1341-321X Impact factor: 2.211