Literature DB >> 12525152

LytG of Bacillus subtilis is a novel peptidoglycan hydrolase: the major active glucosaminidase.

Gavin J Horsburgh1, Abdelmadjid Atrih, Michael P Williamson, Simon J Foster.   

Abstract

LytG (YubE) of Bacillus subtilis is a novel 32 kDa autolysin produced during vegetative growth under the control of Esigma(A) RNA polymerase. Muropeptide analysis of vegetative cells of B. subtilis revealed LytG to be the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Overexpression and purification of LytG allowed its biochemical characterization. Despite sequence homology suggesting muramidase activity, LytG is a novel glucosaminidase with exoenzyme activity and may form part of a novel family of autolysins. It is involved in cell division, lysis, and motility on swarm plates.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12525152     DOI： 10.1021/bi020498c

Source DB:  PubMed          Journal:  Biochemistry        ISSN： 0006-2960            Impact factor:   3.162


  18 in total

1.  YneA, an SOS-induced inhibitor of cell division in Bacillus subtilis, is regulated posttranslationally and requires the transmembrane region for activity.

Authors:  Allison H Mo; William F Burkholder
Journal:  J Bacteriol       Date:  2010-04-16       Impact factor: 3.490

2.  The Enterococcus hirae Mur-2 enzyme displays N-acetylglucosaminidase activity.

Authors:  Catherine Eckert; Sophie Magnet; Stéphane Mesnage
Journal:  FEBS Lett       Date:  2007-01-22       Impact factor: 4.124

Review 3.  The SPOR Domain, a Widely Conserved Peptidoglycan Binding Domain That Targets Proteins to the Site of Cell Division.

Authors:  Atsushi Yahashiri; Matthew A Jorgenson; David S Weiss
Journal:  J Bacteriol       Date:  2017-06-27       Impact factor: 3.490

4.  Diamide Inhibitors of the Bacillus subtilis N-Acetylglucosaminidase LytG That Exhibit Antibacterial Activity.

Authors:  Saman Nayyab; Mary O'Connor; Jennifer Brewster; James Gravier; Mitchell Jamieson; Ethan Magno; Ryan D Miller; Drew Phelan; Keyana Roohani; Paul Williard; Amit Basu; Christopher W Reid
Journal:  ACS Infect Dis       Date:  2017-05-08       Impact factor: 5.084

5.  Functional analysis of AtlA, the major N-acetylglucosaminidase of Enterococcus faecalis.

Authors:  Catherine Eckert; Maxime Lecerf; Lionel Dubost; Michel Arthur; Stéphane Mesnage
Journal:  J Bacteriol       Date:  2006-10-13       Impact factor: 3.490

6.  Identification and Characterization of a Cell Wall Hydrolase for Sporangiospore Maturation in Actinoplanes missouriensis.

Authors:  Kyota Mitsuyama; Takeaki Tezuka; Yasuo Ohnishi
Journal:  J Bacteriol       Date:  2019-11-20       Impact factor: 3.490

7.  Anti-bacterial glycosyl triazoles - Identification of an N-acetylglucosamine derivative with bacteriostatic activity against Bacillus.

Authors:  Helene Kuhn; Danielle Gutelius; Eimear Black; Christina Nadolny; Amit Basu; Christopher Reid
Journal:  Medchemcomm       Date:  2014-08       Impact factor: 3.597

8.  Transcriptomic analysis of xylan utilization systems in Paenibacillus sp. strain JDR-2.

Authors:  Neha Sawhney; Casey Crooks; Franz St John; James F Preston
Journal:  Appl Environ Microbiol       Date:  2015-02       Impact factor: 4.792

9.  A new D,L-endopeptidase gene product, YojL (renamed CwlS), plays a role in cell separation with LytE and LytF in Bacillus subtilis.

Authors:  Tatsuya Fukushima; Anahita Afkham; Shin-Ichirou Kurosawa; Taichi Tanabe; Hiroki Yamamoto; Junichi Sekiguchi
Journal:  J Bacteriol       Date:  2006-08       Impact factor: 3.490

10.  Bacillus subtilis pellicle formation proceeds through genetically defined morphological changes.

Authors:  Kazuo Kobayashi
Journal:  J Bacteriol       Date:  2007-04-27       Impact factor: 3.490
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.