Literature DB >> 12524073

The Ontario Uterine Fibroid Embolization Trial. Part 1. Baseline patient characteristics, fibroid burden, and impact on life.

Gaylene Pron1, Marsha Cohen, Jennifer Soucie, Greg Garvin, Leslie Vanderburgh, Stuart Bell.   

Abstract

OBJECTIVE: To determine baseline characteristics of women undergoing uterine artery embolization (UAE) for symptomatic fibroids.
DESIGN: Multicenter, prospective, single-arm clinical treatment trial.
SETTING: Eight Ontario university and community hospitals. PATIENT(S): Five hundred fifty-five women undergoing UAE for fibroids. INTERVENTION(S): Baseline questionnaires completed before UAE. MAIN OUTCOME MEASURE(S): Questionnaires were analyzed for demographic, medical, and gynecologic histories. Fibroid symptoms, impact of symptoms, previous consultations, and treatments were also analyzed. RESULT(S): The Ontario cohort (66% white, 23% black, 11% other races) had an average age of 43. Thirty-one percent were under age 40. Most women were university educated (68%) and working outside the home (85%). Women reported heavy menstrual bleeding (80%), urinary urgency/frequency (73%), pain during intercourse (41%), and work absences (40%). They experienced fibroid-related symptoms for an average of 5 years and consulted with on average of three gynecologists before UAE. High fibroid life-impact scores were reported by 58%. Black women were significantly younger (40.7 vs. 44.0 years), more likely to experience symptoms longer (7 vs. 5 years), and more likely to undergo myomectomy before UAE (24% vs. 9%) than white women. CONCLUSION(S): Our study illustrates that large numbers of women with highly symptomatic fibroid disease are averse to surgery despite their burden of suffering and are actively seeking alternatives to hysterectomy.

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Mesh:

Year:  2003        PMID: 12524073     DOI: 10.1016/s0015-0282(02)04539-9

Source DB:  PubMed          Journal:  Fertil Steril        ISSN: 0015-0282            Impact factor:   7.329


  22 in total

1.  Uterine artery embolisation versus hysterectomy for leiomyomas: primary and 2-year follow-up results of a randomised prospective clinical trial.

Authors:  Anu Ruuskanen; Maritta Hippeläinen; Petri Sipola; Hannu Manninen
Journal:  Eur Radiol       Date:  2010-06-06       Impact factor: 5.315

2.  Information-seeking behavior of women in their path to an innovative alternate treatment for symptomatic uterine fibroids.

Authors:  Kalyani Ankem
Journal:  J Med Libr Assoc       Date:  2007-04

3.  Pregnancy after uterine artery embolization for fibroids.

Authors:  Sukhbir S Singh; Risa Bordman; Nicholas Leyland
Journal:  Can Fam Physician       Date:  2007-02       Impact factor: 3.275

4.  Vitamin D and uterine leiomyoma among a sample of US women: Findings from NHANES, 2001-2006.

Authors:  Susanna D Mitro; Ami R Zota
Journal:  Reprod Toxicol       Date:  2015-06-03       Impact factor: 3.143

Review 5.  Current evidence on uterine embolization for fibroids.

Authors:  James B Spies
Journal:  Semin Intervent Radiol       Date:  2013-12       Impact factor: 1.513

6.  Preparation and characterization of ketoprofen-loaded microspheres for embolization.

Authors:  Chao Zhou; Daichao Cui; Yuan Zhang; Huiyan Yuan; Tianyuan Fan
Journal:  J Mater Sci Mater Med       Date:  2011-11-22       Impact factor: 3.896

7.  Characteristics indicating adenomyosis coexisting with leiomyomas: a case-control study.

Authors:  F Andrei Taran; Amy L Weaver; Charles C Coddington; Elizabeth A Stewart
Journal:  Hum Reprod       Date:  2010-02-22       Impact factor: 6.918

8.  The effect of uterine fibroid embolization on lower urinary tract symptoms.

Authors:  David Shveiky; Cheryl B Iglesia; Danielle D Antosh; Bela I Kudish; Joanna Peterson; Chun-Chih Huang; Chun-Chin Huang; James B Spies
Journal:  Int Urogynecol J       Date:  2012-12-18       Impact factor: 2.894

9.  [State and development of uterine myoma embolization in Germany].

Authors:  T F Jakobs; T K Helmberger; M F Reiser
Journal:  Radiologe       Date:  2003-08       Impact factor: 0.635

10.  The relationship between uterine leiomyomata and pelvic floor symptoms.

Authors:  Christina E Dancz; Priyanka Kadam; Carrie Li; Kristen Nagata; Begüm Özel
Journal:  Int Urogynecol J       Date:  2013-08-07       Impact factor: 2.894

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