Literature DB >> 12523487

Effect of antidepressant drugs on the hypothalamic-pituitary-adrenal axis activity and glucocorticoid receptor function.

Bogusława Budziszewska1.   

Abstract

Hyperactivity of hypothalamic-pituitary-adrenal (HPA) axis is the main biochemical change, besides disturbed monoaminergic neurotransmission, observed in the patients suffering from a major depression. High incidence of depression in Cushing's syndrome as well as antidepressant effects of adrenocortical enzyme inhibitors in major depression support hypothesis that hyperactivity of HPA axis may be involved in pathogenesis of depression.

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Year:  2002        PMID： 12523487

Source DB:  PubMed          Journal:  Pol J Pharmacol        ISSN： 1230-6002


  8 in total

1.  Effect of chronic treatment with ladostigil (TV-3326) on anxiogenic and depressive-like behaviour and on activity of the hypothalamic-pituitary-adrenal axis in male and female prenatally stressed rats.

Authors:  Tatyana Poltyrev; Elena Gorodetsky; Corina Bejar; Donna Schorer-Apelbaum; Marta Weinstock
Journal:  Psychopharmacology (Berl)       Date:  2005-10-15       Impact factor: 4.530

2.  Antidepressants reverse corticosterone-mediated decrease in brain-derived neurotrophic factor expression: differential regulation of specific exons by antidepressants and corticosterone.

Authors:  Y Dwivedi; H S Rizavi; G N Pandey
Journal:  Neuroscience       Date:  2006-02-24       Impact factor: 3.590

3.  YL-0919, a dual 5-HT1A partial agonist and SSRI, produces antidepressant- and anxiolytic-like effects in rats subjected to chronic unpredictable stress.

Authors:  Yu-Hua Ran; Xiao-Xu Hu; Yu-Lu Wang; Nan Zhao; Li-Ming Zhang; Hua-Xia Liu; Yun-Feng Li
Journal:  Acta Pharmacol Sin       Date:  2017-08-31       Impact factor: 6.150

4.  Antidepressants, but not antipsychotics, modulate GR function in human whole blood: an insight into molecular mechanisms.

Authors:  L A Carvalho; B A Garner; T Dew; H Fazakerley; C M Pariante
Journal:  Eur Neuropsychopharmacol       Date:  2010-03-15       Impact factor: 4.600

5.  Total flavonoids extracted from xiaobuxin-tang on the hyperactivity of hypothalamic-pituitary-adrenal axis in chronically stressed rats.

Authors:  Lei An; You-Zhi Zhang; Xin-Min Liu; Neng-Jiang Yu; Hong-Xia Chen; Nan Zhao; Li Yuan; Yun-Feng Li
Journal:  Evid Based Complement Alternat Med       Date:  2011-06-05       Impact factor: 2.629

6.  Zuogui Jiangtang Jieyu Formulation Prevents Hyperglycaemia and Depressive-Like Behaviour in Rats by Reducing the Glucocorticoid Level in Plasma and Hippocampus.

Authors:  YuHong Wang; Hui Yang; Wei Li; Pan Meng; YuanShan Han; Xiuli Zhang; DeLiang Cao; Yuansheng Tan
Journal:  Evid Based Complement Alternat Med       Date:  2015-07-27       Impact factor: 2.629

7.  Hyperactivity of Hypothalamic-Pituitary-Adrenal Axis Due to Dysfunction of the Hypothalamic Glucocorticoid Receptor in Sigma-1 Receptor Knockout Mice.

Authors:  Tingting Di; Suyun Zhang; Juan Hong; Tingting Zhang; Ling Chen
Journal:  Front Mol Neurosci       Date:  2017-09-06       Impact factor: 5.639

Review 8.  Insights into a possible role of glucagon-like peptide-1 receptor agonists in the treatment of depression.

Authors:  Jan Detka; Katarzyna Głombik
Journal:  Pharmacol Rep       Date:  2021-05-18       Impact factor: 3.024
  8 in total

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