Literature DB >> 12522524

Antidote review: fomepizole for methanol poisoning.

Mark B Mycyk1, Jerrold B Leikin.   

Abstract

Fomepizole (Antizol) was recently approved by the US Food and Drug Administration for treatment of methanol poisoning. By inhibiting the hepatic enzyme alcohol dehydrogenase, it presents formation of toxic metabolites with far fewer consequences than traditional ethanol therapy. It appears that fomepizole will become standard therapy for methanol intoxication as it is for ethylene glycol poisoning.

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Year:  2003        PMID: 12522524     DOI: 10.1097/00045391-200301000-00015

Source DB:  PubMed          Journal:  Am J Ther        ISSN: 1075-2765            Impact factor:   2.688


  3 in total

1.  Should I stay or should I go?: toxic alcohol case in the emergency department.

Authors:  Constance LeBlanc; Nancy Murphy
Journal:  Can Fam Physician       Date:  2009-01       Impact factor: 3.275

Review 2.  Physiology and pharmacology of alcohol: the imidazobenzodiazepine alcohol antagonist site on subtypes of GABAA receptors as an opportunity for drug development?

Authors:  M Wallner; R W Olsen
Journal:  Br J Pharmacol       Date:  2008-02-18       Impact factor: 8.739

3.  Bibliometric profile of the global scientific research on methanol poisoning (1902-2012).

Authors:  Sa'ed H Zyoud; Samah W Al-Jabi; Waleed M Sweileh; Rahmat Awang; W Stephen Waring
Journal:  J Occup Med Toxicol       Date:  2015-05-03       Impact factor: 2.646

  3 in total

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