Literature DB >> 12522317

Assignment of backbone 1H, 13C, and 15N resonances of the SH2 domain of human Grb14.

Paul J Scharf1, Barbara A Lyons.   

Abstract

The (1)H, (13)C, and (15)N backbone resonance assignments have been made for the Src homology 2 (SH2) domain of the human molecular adapter protein Grb14. The assignments, along with the majority of the non-aromatic side-chain (1)H and (13)C resonances are reported. The SH2 domain has been complexed with a phosphotyrosine-containing peptide (pY766) corresponding to the putative binding site in the fibroblast growth factor receptor (FGFR1). Chemical shift changes upon binding are also reported.

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Year:  2002        PMID： 12522317     DOI： 10.1023/a:1021612725752

Source DB:  PubMed          Journal:  J Biomol NMR        ISSN： 0925-2738            Impact factor:   2.835


  7 in total

1.  Solution structure of the Reps1 EH domain and characterization of its binding to NPF target sequences.

Authors:  S Kim; D N Cullis; L A Feig; J D Baleja
Journal:  Biochemistry       Date:  2001-06-12       Impact factor: 3.162

2.  Structural determinants of the interaction between the erbB2 receptor and the Src homology 2 domain of Grb7.

Authors:  P W Janes; M Lackmann; W B Church; G M Sanderson; R L Sutherland; R J Daly
Journal:  J Biol Chem       Date:  1997-03-28       Impact factor: 5.157

3.  The cloning of Grb10 reveals a new family of SH2 domain proteins.

Authors:  J Ooi; V Yajnik; D Immanuel; M Gordon; J J Moskow; A M Buchberg; B Margolis
Journal:  Oncogene       Date:  1995-04-20       Impact factor: 9.867

Review 4.  Pulsed field gradient multi-dimensional NMR methods for the study of protein structure and dynamics in solution.

Authors:  L E Kay
Journal:  Prog Biophys Mol Biol       Date:  1995       Impact factor: 3.667

5.  Identification of Tek/Tie2 binding partners. Binding to a multifunctional docking site mediates cell survival and migration.

Authors:  N Jones; Z Master; J Jones; D Bouchard; Y Gunji; H Sasaki; R Daly; K Alitalo; D J Dumont
Journal:  J Biol Chem       Date:  1999-10-22       Impact factor: 5.157

6.  Cloning and characterization of GRB14, a novel member of the GRB7 gene family.

Authors:  R J Daly; G M Sanderson; P W Janes; R L Sutherland
Journal:  J Biol Chem       Date:  1996-05-24       Impact factor: 5.157

7.  Association of fibroblast growth factor receptor 1 with the adaptor protein Grb14. Characterization of a new receptor binding partner.

Authors:  J F Reilly; G Mickey; P A Maher
Journal:  J Biol Chem       Date:  2000-03-17       Impact factor: 5.157
  7 in total
  1 in total

1.  Solution structure of the human Grb14-SH2 domain and comparison with the structures of the human Grb7-SH2/erbB2 peptide complex and human Grb10-SH2 domain.

Authors:  Paul J Scharf; Jill Witney; Roger Daly; Barbara A Lyons
Journal:  Protein Sci       Date:  2004-09       Impact factor: 6.725
  1 in total

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