| Literature DB >> 12522061 |
Mariko Kohmoto1, Yasuhiro Ikeda, Eiji Sato, Yorihiro Nishimura, Yasuo Inoshima, Masayuki Shimojima, Yukinobu Tohya, Takeshi Mikami, Takayuki Miyazawa.
Abstract
Four of six specific pathogen-free cats were infected after intravaginal exposure to molecularly cloned lymphotropic but non-Crandell feline kidney (CRFK)-tropic feline immunodeficiency virus strain TM2 and its AP-1 deletion mutant. The sequences of the env V3-to-V5 region which defines the CRFK tropism were unchanged in the infected cats through the infection. These data suggest that the strain was transmitted across the mucosal epithelium without a broadening of cell tropism.Entities:
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Year: 2003 PMID: 12522061 PMCID: PMC145290 DOI: 10.1128/cdli.10.1.185-188.2003
Source DB: PubMed Journal: Clin Diagn Lab Immunol ISSN: 1071-412X