Literature DB >> 12520132

Transformation of Cinchona alkaloids into 1-N-oxide derivatives by endophytic Xylaria sp isolated from Cinchona pubescens.

Hirotaka Shibuya1, Chinami Kitamura, Shoji Maehara, Marie Nagahata, Hendig Winarno, Partomuan Simanjuntak, Hye-Sook Kim, Yusuke Wataya, Kazuyoshi Ohashi.   

Abstract

The microbial transformation of four Cinchona alkaloids (quinine, quinidine, cinchonidine, and cinchonine) by endophytic fungi isolated from Cinchona pubescens was investigated. The endophytic filamentous fungus Xylaria sp. was found to transform the Cinchona alkaloids into their 1-N-oxide derivatives.

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Year:  2003        PMID： 12520132     DOI： 10.1248/cpb.51.71

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  11 in total

1.  Composition of endophytic fungi living in Cinchona ledgeriana (Rubiaceae).

Authors:  Shoji Maehara; Partomuan Simanjuntak; Kazuyoshi Ohashi; Hirotaka Shibuya
Journal:  J Nat Med       Date:  2010-04       Impact factor: 2.343

2.  Composition of the endophytic filamentous fungi isolated from the tea plant Camellia sinensis.

Authors:  Andria Agusta; Kazuyoshi Ohashi; Hirotaka Shibuya
Journal:  J Nat Med       Date:  2006-04-14       Impact factor: 2.343

3.  Endophytic biocatalysts with enoate reductase activity isolated from Mentha pulegium.

Authors:  Facundo Marconi; María Laura Umpiérrez; David Gonzalez; Sonia Rodríguez Giordano; Paula Rodriguez
Journal:  World J Microbiol Biotechnol       Date:  2018-03-17       Impact factor: 3.312

4.  Ability of endophytic filamentous fungi associated with Cinchona ledgeriana to produce Cinchona alkaloids.

Authors:  Shoji Maehara; Partomuan Simanjuntak; Yoshihide Maetani; Chinami Kitamura; Kazuyoshi Ohashi; Hirotaka Shibuya
Journal:  J Nat Med       Date:  2012-08-11       Impact factor: 2.343

5.  Composition of the endophytic filamentous fungi associated with Cinchona ledgeriana seeds and production of Cinchona alkaloids.

Authors:  Shoji Maehara; Andria Agusta; Chinami Kitamura; Kazuyoshi Ohashi; Hirotaka Shibuya
Journal:  J Nat Med       Date:  2015-12-08       Impact factor: 2.343

6.  The use of endophytes to obtain bioactive compounds and their application in biotransformation process.

Authors:  Mariana Recco Pimentel; Gustavo Molina; Ana Paula Dionísio; Mário Roberto Maróstica Junior; Gláucia Maria Pastore
Journal:  Biotechnol Res Int       Date:  2010-09-26

7.  Diversity and Ginsenoside Biotransformation Potential of Cultivable Endophytic Fungi Associated With Panax bipinnatifidus var. bipinnatifidus in Qinling Mountains, China.

Authors:  Chao An; Saijian Ma; Xinwei Shi; Chen Liu; Hao Ding; Wenjiao Xue
Journal:  Front Pharmacol       Date:  2022-04-04       Impact factor: 5.988

8.  Unexpectedly High Beta-Diversity of Root-Associated Fungal Communities in the Bolivian Andes.

Authors:  Christopher J Barnes; Carla Maldonado; Tobias G Frøslev; Alexandre Antonelli; Nina Rønsted
Journal:  Front Microbiol       Date:  2016-08-31       Impact factor: 5.640

Review 9.  Microbial Biotransformation to Obtain New Antifungals.

Authors:  Luiz F Bianchini; Maria F C Arruda; Sergio R Vieira; Patrícia M S Campelo; Ana M T Grégio; Edvaldo A R Rosa
Journal:  Front Microbiol       Date:  2015-12-24       Impact factor: 5.640

10.  Diversity and Antifungal Activity of Endophytic Fungi Associated with Camellia oleifera.

Authors:  Jinxiu Yu; Ying Wu; Zhen He; Mi Li; Kaiming Zhu; Bida Gao
Journal:  Mycobiology       Date:  2018-04-23       Impact factor: 1.858
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