Literature DB >> 12519929

Complement C5a in the sepsis syndrome--too much of a good thing?

Craig Gerard1.   

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Year:  2003        PMID: 12519929     DOI: 10.1056/NEJMcibr022995

Source DB:  PubMed          Journal:  N Engl J Med        ISSN: 0028-4793            Impact factor:   91.245


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  27 in total

1.  Early complementopathy after multiple injuries in humans.

Authors:  Anne-Maud Burk; Myriam Martin; Michael A Flierl; Daniel Rittirsch; Matthias Helm; Lorenz Lampl; Uwe Bruckner; Gregory L Stahl; Anna M Blom; Mario Perl; Florian Gebhard; Markus Huber-Lang
Journal:  Shock       Date:  2012-04       Impact factor: 3.454

Review 2.  Acute lung injury and the acute respiratory distress syndrome: four decades of inquiry into pathogenesis and rational management.

Authors:  Michael A Matthay; Guy A Zimmerman
Journal:  Am J Respir Cell Mol Biol       Date:  2005-10       Impact factor: 6.914

3.  Stages of meningococcal sepsis simulated in vitro, with emphasis on complement and Toll-like receptor activation.

Authors:  Bernt Christian Hellerud; Jørgen Stenvik; Terje Espevik; John D Lambris; Tom Eirik Mollnes; Petter Brandtzaeg
Journal:  Infect Immun       Date:  2008-06-30       Impact factor: 3.441

4.  Functions of the complement components C3 and C5 during sepsis.

Authors:  Michael A Flierl; Daniel Rittirsch; Brian A Nadeau; Danielle E Day; Firas S Zetoune; J Vidya Sarma; Markus S Huber-Lang; Peter A Ward
Journal:  FASEB J       Date:  2008-06-27       Impact factor: 5.191

Review 5.  Harmful molecular mechanisms in sepsis.

Authors:  Daniel Rittirsch; Michael A Flierl; Peter A Ward
Journal:  Nat Rev Immunol       Date:  2008-10       Impact factor: 53.106

6.  Monocyte upregulation of podoplanin during early sepsis induces complement inhibitor release to protect liver function.

Authors:  Zhanli Xie; Bojing Shao; Christopher Hoover; Michael McDaniel; Jianhua Song; Miao Jiang; Zhenni Ma; Fei Yang; Jingjing Han; Xia Bai; Changgeng Ruan; Lijun Xia
Journal:  JCI Insight       Date:  2020-07-09

Review 7.  Postinjury Inflammation and Organ Dysfunction.

Authors:  Angela Sauaia; Frederick A Moore; Ernest E Moore
Journal:  Crit Care Clin       Date:  2017-01       Impact factor: 3.598

8.  C5aR-antagonist significantly reduces the deleterious effect of a blunt chest trauma on fracture healing.

Authors:  Stefan Recknagel; Ronny Bindl; Julian Kurz; Tim Wehner; Philipp Schoengraf; Christian Ehrnthaller; Hongchang Qu; Florian Gebhard; Markus Huber-Lang; John D Lambris; Lutz Claes; Anita Ignatius
Journal:  J Orthop Res       Date:  2011-09-15       Impact factor: 3.494

9.  Impaired neutrophil extracellular trap (NET) formation: a novel innate immune deficiency of human neonates.

Authors:  Christian C Yost; Mark J Cody; Estelle S Harris; Nathan L Thornton; Alison M McInturff; Mark L Martinez; Nancy B Chandler; Christopher K Rodesch; Kurt H Albertine; Cathy A Petti; Andrew S Weyrich; Guy A Zimmerman
Journal:  Blood       Date:  2009-02-12       Impact factor: 22.113

10.  Inhibition of complement C5a prevents breakdown of the blood-brain barrier and pituitary dysfunction in experimental sepsis.

Authors:  Michael A Flierl; Philip F Stahel; Daniel Rittirsch; Markus Huber-Lang; Andreas D Niederbichler; L Marco Hoesel; Basel M Touban; Steven J Morgan; Wade R Smith; Peter A Ward; Kyros Ipaktchi
Journal:  Crit Care       Date:  2009-02-06       Impact factor: 9.097

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