Literature DB >> 12517881

Thymidine-dependent small-colony variants of Staphylococcus aureus exhibit gross morphological and ultrastructural changes consistent with impaired cell separation.

Barbara C Kahl1, Gunnar Belling, Rudolf Reichelt, Mathias Herrmann, Richard A Proctor, Georg Peters.   

Abstract

Thymidine-dependent small-colony variants (SCV) of Staphylococcus aureus exhibited unusual colony morphology with "fried-egg" or pinpoint white colonies on agar plates and pleomorphic cocci as determined by Gram staining. Electron microscopy revealed enlarged cocci with incomplete or multiple cross walls consistent with impaired cell separation. Fried-egg SCV phenotypes could be reversed by thymidine supplementation.

Entities:  

Mesh:

Substances:

Year:  2003        PMID: 12517881      PMCID: PMC149606          DOI: 10.1128/JCM.41.1.410-413.2003

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN: 0095-1137            Impact factor:   5.948


  10 in total

1.  Patterns of multidrug resistance among methicillin-resistant hospital isolates of coagulase-positive and coagulase-negative staphylococci collected in the international multicenter study RESIST in 1997 and 1998.

Authors:  I Santos Sanches; R Mato; H de Lencastre; A Tomasz
Journal:  Microb Drug Resist       Date:  2000       Impact factor: 3.431

Review 2.  Staphylococcus aureus infections.

Authors:  F D Lowy
Journal:  N Engl J Med       Date:  1998-08-20       Impact factor: 91.245

3.  Recovery of small colony variants of Staphylococcus aureus following gentamicin bead placement for osteomyelitis.

Authors:  C von Eiff; D Bettin; R A Proctor; B Rolauffs; N Lindner; W Winkelmann; G Peters
Journal:  Clin Infect Dis       Date:  1997-11       Impact factor: 9.079

4.  Persistent infection with small colony variant strains of Staphylococcus aureus in patients with cystic fibrosis.

Authors:  B Kahl; M Herrmann; A S Everding; H G Koch; K Becker; E Harms; R A Proctor; G Peters
Journal:  J Infect Dis       Date:  1998-04       Impact factor: 5.226

5.  Staphylocidal action of thrombin-induced platelet microbicidal protein is not solely dependent on transmembrane potential.

Authors:  S P Koo; A S Bayer; H G Sahl; R A Proctor; M R Yeaman
Journal:  Infect Immun       Date:  1996-03       Impact factor: 3.441

6.  Gentamicin-resistant menadione and hemin auxotrophic Staphylococcus aureus persist within cultured endothelial cells.

Authors:  J M Balwit; P van Langevelde; J M Vann; R A Proctor
Journal:  J Infect Dis       Date:  1994-10       Impact factor: 5.226

7.  Prevalence of thymidine-dependent Staphylococcus aureus in patients with cystic fibrosis.

Authors:  P H Gilligan; P A Gage; D F Welch; M J Muszynski; K R Wait
Journal:  J Clin Microbiol       Date:  1987-07       Impact factor: 5.948

Review 8.  Variant subpopulations of Staphylococcus aureus as cause of persistent and recurrent infections.

Authors:  R A Proctor; J M Balwit; O Vesga
Journal:  Infect Agents Dis       Date:  1994-12

9.  Trimethoprim-induced structural alterations in Staphylococcus aureus and the recovery of bacteria in drug-free medium.

Authors:  T Nishino; J Wecke; D Krüger; P Giesbrecht
Journal:  J Antimicrob Chemother       Date:  1987-02       Impact factor: 5.790

10.  Fatal case due to methicillin-resistant Staphylococcus aureus small colony variants in an AIDS patient.

Authors:  H Seifert; C von Eiff; G Fätkenheuer
Journal:  Emerg Infect Dis       Date:  1999 May-Jun       Impact factor: 6.883

  10 in total
  43 in total

1.  Altered Competitive Fitness, Antimicrobial Susceptibility, and Cellular Morphology in a Triclosan-Induced Small-Colony Variant of Staphylococcus aureus.

Authors:  Sarah Forbes; Joe Latimer; Abdulrahman Bazaid; Andrew J McBain
Journal:  Antimicrob Agents Chemother       Date:  2015-06-01       Impact factor: 5.191

Review 2.  Clinical Significance and Pathogenesis of Staphylococcal Small Colony Variants in Persistent Infections.

Authors:  Barbara C Kahl; Karsten Becker; Bettina Löffler
Journal:  Clin Microbiol Rev       Date:  2016-04       Impact factor: 26.132

3.  Attenuated virulence and biofilm formation in Staphylococcus aureus following sublethal exposure to triclosan.

Authors:  Joe Latimer; Sarah Forbes; Andrew J McBain
Journal:  Antimicrob Agents Chemother       Date:  2012-03-19       Impact factor: 5.191

Review 4.  [Replacement of infected knee and hip endoprostheses].

Authors:  M Militz; V Bühren
Journal:  Chirurg       Date:  2010-04       Impact factor: 0.955

5.  Optimized In Vitro Antibiotic Susceptibility Testing Method for Small-Colony Variant Staphylococcus aureus.

Authors:  Mimi R Precit; Daniel J Wolter; Adam Griffith; Julia Emerson; Jane L Burns; Lucas R Hoffman
Journal:  Antimicrob Agents Chemother       Date:  2016-01-04       Impact factor: 5.191

6.  Characterization of clinical Enterococcus faecalis small-colony variants.

Authors:  Nele Wellinghausen; Indranil Chatterjee; Anja Berger; Andrea Niederfuehr; Richard A Proctor; Barbara C Kahl
Journal:  J Clin Microbiol       Date:  2009-07-15       Impact factor: 5.948

7.  Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype and revertant strains.

Authors:  Hoang Anh Nguyen; Olivier Denis; Anne Vergison; Anne Theunis; Paul M Tulkens; Marc J Struelens; Françoise Van Bambeke
Journal:  Antimicrob Agents Chemother       Date:  2009-02-02       Impact factor: 5.191

8.  Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus.

Authors:  Tobias Norström; Jonas Lannergård; Diarmaid Hughes
Journal:  Antimicrob Agents Chemother       Date:  2007-10-08       Impact factor: 5.191

9.  Isolation and characterization of small-colony variants of Ornithobacterium rhinotracheale.

Authors:  Mohammad Zahra; Miro Ferreri; Rashad Alkasir; Jinhua Yin; Bo Han; Jingliang Su
Journal:  J Clin Microbiol       Date:  2013-07-17       Impact factor: 5.948

10.  Characterization of small-colony variants of Enterococcus faecalis isolated from chickens with amyloid arthropathy.

Authors:  Andreas Petersen; Mark S Chadfield; Jens P Christensen; Henrik Christensen; Magne Bisgaard
Journal:  J Clin Microbiol       Date:  2008-06-25       Impact factor: 5.948

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.