Literature DB >> 12517706

Cell polarity: Par6, aPKC and cytoskeletal crosstalk.

Sandrine Etienne-Manneville1, Alan Hall.   

Abstract

Par6 and atypical protein kinase C are key players in the establishment of cell polarity. First discovered in Caenorhabditis elegans, the function of this protein complex is conserved in all multicellular organisms. Recent work is beginning to throw light on how it converts information generated by extracellular cues into intracellular asymmetry.

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Year:  2003        PMID： 12517706     DOI： 10.1016/s0955-0674(02)00005-4

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN： 0955-0674            Impact factor:   8.382


  110 in total

1.  Polarity-regulating kinase partitioning-defective 1b (PAR1b) phosphorylates guanine nucleotide exchange factor H1 (GEF-H1) to regulate RhoA-dependent actin cytoskeletal reorganization.

Authors:  Yukie Yamahashi; Yasuhiro Saito; Naoko Murata-Kamiya; Masanori Hatakeyama
Journal:  J Biol Chem       Date:  2011-11-09       Impact factor: 5.157

2.  The PB1 domain and the PC motif-containing region are structurally similar protein binding modules.

Authors:  Sosuke Yoshinaga; Motoyuki Kohjima; Kenji Ogura; Masashi Yokochi; Ryu Takeya; Takashi Ito; Hideki Sumimoto; Fuyuhiko Inagaki
Journal:  EMBO J       Date:  2003-10-01       Impact factor: 11.598

3.  Inhibition of SRC family kinases and non-classical protein kinases C induce a reeler-like malformation of cortical plate development.

Authors:  Yves Jossin; Masuhara Ogawa; Christine Metin; Fadel Tissir; André M Goffinet
Journal:  J Neurosci       Date:  2003-10-29       Impact factor: 6.167

4.  Nucleotide exchange factor ECT2 interacts with the polarity protein complex Par6/Par3/protein kinase Czeta (PKCzeta) and regulates PKCzeta activity.

Authors:  Xiu-Fen Liu; Hiroshi Ishida; Razi Raziuddin; Toru Miki
Journal:  Mol Cell Biol       Date:  2004-08       Impact factor: 4.272

Review 5.  Breaking into the epithelial apical-junctional complex--news from pathogen hackers.

Authors:  Roger Vogelmann; Manuel R Amieva; Stanley Falkow; W James Nelson
Journal:  Curr Opin Cell Biol       Date:  2004-02       Impact factor: 8.382

6.  Coherent angular motion in the establishment of multicellular architecture of glandular tissues.

Authors:  Kandice Tanner; Hidetoshi Mori; Rana Mroue; Alexandre Bruni-Cardoso; Mina J Bissell
Journal:  Proc Natl Acad Sci U S A       Date:  2012-01-25       Impact factor: 11.205

7.  The Dishevelled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility.

Authors:  Maki Ishida-Takagishi; Atsushi Enomoto; Naoya Asai; Kaori Ushida; Takashi Watanabe; Takahiko Hashimoto; Takuya Kato; Liang Weng; Shinji Matsumoto; Masato Asai; Yoshiki Murakumo; Kozo Kaibuchi; Akira Kikuchi; Masahide Takahashi
Journal:  Nat Commun       Date:  2012-05-29       Impact factor: 14.919

8.  Combinatorial cell-specific regulation of GSK3 directs cell differentiation and polarity in Dictyostelium.

Authors:  Leung Kim; Joseph Brzostowski; Amit Majithia; Nam-Sihk Lee; Vanessa McMains; Alan R Kimmel
Journal:  Development       Date:  2011-02       Impact factor: 6.868

9.  A novel functional polymorphism (-336A/G) in the promoter of the partitioning-defective protein-6alpha gene is associated with increased glucose tolerance and lower concentrations of serum non-esterified fatty acids.

Authors:  P Weyrich; R Lammers; A Fritsche; F Machicao; H-U Häring; N Stefan
Journal:  Diabetologia       Date:  2005-03-03       Impact factor: 10.122

Review 10.  Protein kinase C iota: human oncogene, prognostic marker and therapeutic target.

Authors:  Alan P Fields; Roderick P Regala
Journal:  Pharmacol Res       Date:  2007-05-05       Impact factor: 7.658
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