| Literature DB >> 1251575 |
D Roelcke, W Ebert, H P Geisen.
Abstract
A monoclonal IgM(kappa) anti-Pr cold agglutinin occurring after a rubella infection is shown to have the 'new' anti-Pr subspecificity anti-Pr3. Pr3 determinants are found on cat and sheep erythrocytes which lack Pr1 and Pr2 determinants. By carbodiimide treatment of human erythrocyte glycoproteins, which causes intramolecular coupling of N-acetylneuraminic acid carboxyl groups and nucleophilic centers of the glycoprotein backbone, Pr3 antigen activity is strongly increased, while Pr1 and Pr2 determinants are inactivated.Entities:
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Year: 1976 PMID: 1251575 DOI: 10.1111/j.1423-0410.1976.tb02802.x
Source DB: PubMed Journal: Vox Sang ISSN: 0042-9007 Impact factor: 2.144