Literature DB >> 12514724

Advances in the use of synthetic combinatorial chemistry: mixture-based libraries.

Clemencia Pinilla1, Jon R Appel, Eva Borràs, Richard A Houghten.   

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Year:  2003        PMID： 12514724     DOI： 10.1038/nm0103-118

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


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  36 in total

1.  Potent antimicrobial small molecules screened as inhibitors of tyrosine recombinases and Holliday junction-resolving enzymes.

Authors:  Marc C Rideout; Jeffrey L Boldt; Gabriel Vahi-Ferguson; Peter Salamon; Adel Nefzi; John M Ostresh; Marc Giulianotti; Clemencia Pinilla; Anca M Segall
Journal:  Mol Divers       Date:  2011-09-22       Impact factor: 2.943

2.  Integrating computational and mixture-based screening of combinatorial libraries.

Authors:  Austin B Yongye; Clemencia Pinilla; Jose L Medina-Franco; Marc A Giulianotti; Colette T Dooley; Jon R Appel; Adel Nefzi; Thomas Scior; Richard A Houghten; Karina Martínez-Mayorga
Journal:  J Mol Model       Date:  2010-09-21       Impact factor: 1.810

3.  Generation of diverse 1-imidazolylisoquinolines via silver triflate-catalyzed reaction of 2-alkynylbenzaldoxime with imidazole.

Authors:  Qian Xiao; Shengqing Ye; Danqing Zheng; Ling Zhang; Jie Wu
Journal:  Mol Divers       Date:  2012-01-25       Impact factor: 2.943

4.  Conformational landscape of platinum(II)-tetraamine complexes: DFT and NBO studies.

Authors:  Austin B Yongye; Marc A Giulianotti; Adel Nefzi; Richard A Houghten; Karina Martínez-Mayorga
Journal:  J Comput Aided Mol Des       Date:  2010-03-24       Impact factor: 3.686

5.  ENPDA: an evolutionary structure-based de novo peptide design algorithm.

Authors:  Ignasi Belda; Sergio Madurga; Xavier Llorà; Marc Martinell; Teresa Tarragó; Mireia G Piqueras; Ernesto Nicolás; Ernest Giralt
Journal:  J Comput Aided Mol Des       Date:  2005-11-03       Impact factor: 3.686

6.  Synergy and antagonism of promiscuous inhibition in multiple-compound mixtures.

Authors:  Brian Y Feng; Brian K Shoichet
Journal:  J Med Chem       Date:  2006-04-06       Impact factor: 7.446

7.  Selective agonists and antagonists of formylpeptide receptors: duplex flow cytometry and mixture-based positional scanning libraries.

Authors:  Clemencia Pinilla; Bruce S Edwards; Jon R Appel; Tina Yates-Gibbins; Marc A Giulianotti; Jose L Medina-Franco; Susan M Young; Radleigh G Santos; Larry A Sklar; Richard A Houghten
Journal:  Mol Pharmacol       Date:  2013-06-20       Impact factor: 4.436

Review 8.  Shifting from the single to the multitarget paradigm in drug discovery.

Authors:  José L Medina-Franco; Marc A Giulianotti; Gregory S Welmaker; Richard A Houghten
Journal:  Drug Discov Today       Date:  2013-01-20       Impact factor: 7.851

Review 9.  Cross-reactivity of T lymphocytes in infection and autoimmunity.

Authors:  Thomas Kamradt; Rudolf Volkmer-Engert
Journal:  Mol Divers       Date:  2004       Impact factor: 2.943

10.  The pharmacological properties of a novel MCH1 receptor antagonist isolated from combinatorial libraries.

Authors:  Hiroshi Nagasaki; Shinjae Chung; Colette T Dooley; Zhiwei Wang; Chunying Li; Yumiko Saito; Stewart D Clark; Richard A Houghten; Olivier Civelli
Journal:  Eur J Pharmacol       Date:  2008-11-17       Impact factor: 4.432
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