Literature DB >> 12514700

Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease.

Li-Bang Yang, Kristina Lindholm, Riqiang Yan, Martin Citron, Weiming Xia, Xiao-Li Yang, Thomas Beach, Lucia Sue, Philip Wong, Donald Price, Rena Li, Yong Shen.   

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Year:  2003        PMID： 12514700     DOI： 10.1038/nm0103-3

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


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  300 in total

1.  BACE1 gene promoter single-nucleotide polymorphisms in Alzheimer's disease.

Authors:  Weihui Zhou; Fang Cai; Yu Li; George S Yang; Kathleen D O'Connor; Robert A Holt; Weihong Song
Journal:  J Mol Neurosci       Date:  2010-05-09       Impact factor: 3.444

2.  BACE2 expression increases in human neurodegenerative disease.

Authors:  Christopher J Holler; Robin L Webb; Ashley L Laux; Tina L Beckett; Dana M Niedowicz; Rachel R Ahmed; Yinxing Liu; Christopher R Simmons; Amy L S Dowling; Angela Spinelli; Moshe Khurgel; Steven Estus; Elizabeth Head; Louis B Hersh; M Paul Murphy
Journal:  Am J Pathol       Date:  2011-11-07       Impact factor: 4.307

3.  Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients.

Authors:  Rena Li; Kristina Lindholm; Li-Bang Yang; Xu Yue; Martin Citron; Riqiang Yan; Thomas Beach; Lucia Sue; Marwan Sabbagh; Huaibin Cai; Philip Wong; Donald Price; Yong Shen
Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-20       Impact factor: 11.205

Review 4.  Regulation of α-secretase ADAM10 expression and activity.

Authors:  Kristina Endres; Falk Fahrenholz
Journal:  Exp Brain Res       Date:  2011-10-04       Impact factor: 1.972

Review 5.  Current therapeutic targets for the treatment of Alzheimer's disease.

Authors:  Joshua D Grill; Jeffrey L Cummings
Journal:  Expert Rev Neurother       Date:  2010-05       Impact factor: 4.618

Review 6.  Flavonoids as therapeutic compounds targeting key proteins involved in Alzheimer's disease.

Authors:  Filipa I Baptista; Ana G Henriques; Artur M S Silva; Jens Wiltfang; Odete A B da Cruz e Silva
Journal:  ACS Chem Neurosci       Date:  2014-01-03       Impact factor: 4.418

7.  BACE1 levels by APOE genotype in non-demented and Alzheimer's post-mortem brains.

Authors:  Boris Decourt; Amanda Gonzales; Thomas G Beach; Michael Malek-Ahmadi; Aaron Walker; Lucia Sue; Douglas G Walker; Marwan N Sabbagh
Journal:  Curr Alzheimer Res       Date:  2013-03       Impact factor: 3.498

8.  Cytochrome c oxidase deficiency in neurons decreases both oxidative stress and amyloid formation in a mouse model of Alzheimer's disease.

Authors:  Hirokazu Fukui; Francisca Diaz; Sofia Garcia; Carlos T Moraes
Journal:  Proc Natl Acad Sci U S A       Date:  2007-08-21       Impact factor: 11.205

9.  BACE1 regulates voltage-gated sodium channels and neuronal activity.

Authors:  Doo Yeon Kim; Bryce W Carey; Haibin Wang; Laura A M Ingano; Alexander M Binshtok; Mary H Wertz; Warren H Pettingell; Ping He; Virginia M-Y Lee; Clifford J Woolf; Dora M Kovacs
Journal:  Nat Cell Biol       Date:  2007-06-18       Impact factor: 28.824

Review 10.  Shared cognitive and behavioral impairments in epilepsy and Alzheimer's disease and potential underlying mechanisms.

Authors:  Jeannie Chin; Helen E Scharfman
Journal:  Epilepsy Behav       Date:  2013-01-13       Impact factor: 2.937
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