Literature DB >> 12512413

Osteoarticular grafts in the treatment of OCD of the talus: mosaicplasty versus autologous chondrocyte transplantation.

Sandro Giannini1, Francesca Vannini, Roberto Buda.   

Abstract

Further advancements in articular cartilage transplantation require an understanding of the anatomy, physiology, biomaterials, biology, and cartilage engineering that are fundamental for better results in joint arthroplasty and cartilage repair. Currently, efforts to induce healing and regeneration of cartilage are being directed toward enhancing the natural potential of cartilage to replace the damaged tissue with cells that can generate cartilage. Mosaicplasty and ACT are carried out in the same way, have similar therapeutic indications, and have been demonstrated capable of reconstructing hyaline cartilage with similar clinical results. ACT is the most recent technique and, in the authors' opinion, is preferable in that it is less invasive at the donor site and gives better histologic results because of the reconstruction of a continuous cartilage sheath compared with that achieved by mosaicplasty. Furthermore, with this technique, it is possible to forecast the possibility of improvement owing to further technical and biologic advancements. The authors are currently experimenting with the use of adhesive patches with substitution of the periosteum, resulting in less morbidity. The use of growth factors and new tissue engineering techniques in the future would simplify the methodology, rendering it less invasive and more effective.

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Year:  2002        PMID: 12512413     DOI: 10.1016/s1083-7515(02)00023-2

Source DB:  PubMed          Journal:  Foot Ankle Clin        ISSN: 1083-7515            Impact factor:   1.653


  4 in total

1.  Regenerative treatment in osteochondral lesions of the talus: autologous chondrocyte implantation versus one-step bone marrow derived cells transplantation.

Authors:  Roberto Buda; Francesca Vannini; Francesco Castagnini; Marco Cavallo; Alberto Ruffilli; Laura Ramponi; Gherardo Pagliazzi; Sandro Giannini
Journal:  Int Orthop       Date:  2015-02-08       Impact factor: 3.075

2.  The Role of Magnetic Resonance Imaging in Autologous Matrix-Induced Chondrogenesis for Osteochondral Lesions of the Talus: Analyzing MOCART 1 and 2.0.

Authors:  Fabio A Casari; Christoph Germann; Lizzy Weigelt; Stephan Wirth; Arnd Viehöfer; Jakob Ackermann
Journal:  Cartilage       Date:  2020-08-01       Impact factor: 3.117

3.  A novel implantation technique for engineered osteo-chondral grafts.

Authors:  C Candrian; Andrea Barbero; E Bonacina; S Francioli; M T Hirschmann; S Milz; V Valderrabano; M Heberer; I Martin; M Jakob
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2009-03-21       Impact factor: 4.342

Review 4.  Osteochondral Lesions of the Talus: A Review on Talus Osteochondral Injuries, Including Osteochondritis Dissecans.

Authors:  Juergen Bruns; Christian Habermann; Mathias Werner
Journal:  Cartilage       Date:  2021-01-09       Impact factor: 3.117

  4 in total

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