Literature DB >> 12512155

Pharmacoeconomic evaluation of a patient education letter aimed at reducing long-term prescribing of benzodiazepines.

Julie D Morgan1, David J Wright, Henry Chrystyn.   

Abstract

OBJECTIVE: To determine the economic implications of sending an educational letter to patients, aimed at reducing long-term BDZ prescribing.
METHOD: Letters were sent to 242 patients from 2 general medical practices. BDZ usage and costs were compared in the years before and after intervention using numbers of defined daily dosages (DDDs) prescribed. The cost of intervention implementation was estimated using pharmacist, GP and administrative staff time, plus postage costs. MAIN OUTCOME MEASURES: Number of BDZ DDDs prescribed during the 12-month periods before and after intervention. The cost implications of intervention.
RESULTS: Mean patient age was 67 years, 75% were female and the mean duration of BDZ usage was 19 years. A mean of 337 benzodiazepine DDDs per patient were prescribed during the baseline year. Overall BDZ usage at baseline was increasing by 13%. After receiving the letter, 31% of patients discussed BDZ usage with their GP and 10% had their drug or strength changed. During the year after intervention, a significant reduction of 17% in benzodiazepine usage was observed compared to baseline; 5% of patients ordered no more benzodiazepine prescriptions after receiving the letter. Mean BDZ costs reduced by 1.20 Pounds per patient after intervention. The cost of intervention implementation was 5.54 Pounds per patient, giving a net cost of 4.34 Pounds per patient, or 86.80 Pounds to obtain one BDZ discontinuation.
CONCLUSION: This intervention is effective, simple, and inexpensive. Its minimal cost could be justified given the morbidity associated with the long-term prescribing of benzodiazepines, particularly in the elderly.

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Year:  2002        PMID: 12512155     DOI: 10.1023/a:1021587209529

Source DB:  PubMed          Journal:  Pharm World Sci        ISSN: 0928-1231


  14 in total

Review 1.  The place of benzodiazepines in psychiatric practice.

Authors:  P Tyrer; S Murphy
Journal:  Br J Psychiatry       Date:  1987-12       Impact factor: 9.319

2.  Community survey of long term daytime use of benzodiazepines.

Authors:  N Wright; R Caplan; S Payne
Journal:  BMJ       Date:  1994-07-02

3.  Systematic review of the benzodiazepines. Guidelines for data sheets on diazepam, chlordiazepoxide, medazepam, clorazepate, lorazepam, oxazepam, temazepam, triazolam, nitrazepam, and flurazepam. Committee on the Review of Medicines.

Authors: 
Journal:  Br Med J       Date:  1980-03-29

4.  Drug-related problems in elderly patients admitted to Tayside hospitals, methods for prevention and subsequent reassessment.

Authors:  G Cunningham; T R Dodd; D J Grant; M E McMurdo; R M Richards
Journal:  Age Ageing       Date:  1997-09       Impact factor: 10.668

5.  The long-term use of benzodiazepines: patients' views, accounts and experiences.

Authors:  G Barter; M Cormack
Journal:  Fam Pract       Date:  1996-12       Impact factor: 2.267

Review 6.  Benzodiazepine dependence. Avoidance and withdrawal.

Authors:  S Marriott; P Tyrer
Journal:  Drug Saf       Date:  1993-08       Impact factor: 5.606

7.  Association of road-traffic accidents with benzodiazepine use.

Authors:  F Barbone; A D McMahon; P G Davey; A D Morris; I C Reid; D G McDevitt; T M MacDonald
Journal:  Lancet       Date:  1998-10-24       Impact factor: 79.321

8.  Admissions to hospital due to drugs.

Authors:  N Hurwitz
Journal:  Br Med J       Date:  1969-03-01

9.  Drugs and falls in older people: a systematic review and meta-analysis: I. Psychotropic drugs.

Authors:  R M Leipzig; R G Cumming; M E Tinetti
Journal:  J Am Geriatr Soc       Date:  1999-01       Impact factor: 5.562

10.  Long term use of benzodiazepines: the views of patients.

Authors:  M B King; J Gabe; P Williams; E K Rodrigo
Journal:  Br J Gen Pract       Date:  1990-05       Impact factor: 5.386

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  7 in total

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Authors: 
Journal:  CNS Drugs       Date:  2003       Impact factor: 5.749

2.  Tapering off benzodiazepines in long-term users: an economic evaluation.

Authors:  Richard C Oude Voshaar; Paul F M Krabbe; Wim J M J Gorgels; Eddy M M Adang; Anton J L M van Balkom; Eloy H van de Lisdonk; Frans G Zitman
Journal:  Pharmacoeconomics       Date:  2006       Impact factor: 4.981

3.  Engaging patients in de-implementation interventions to reduce low-value clinical care: a systematic review and meta-analysis.

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Review 4.  Pharmacist interventions to deprescribe opioids and benzodiazepines in older adults: A rapid review.

Authors:  Joshua D Niznik; Brendan J Collins; Lori T Armistead; Claire K Larson; Casey J Kelley; Tamera D Hughes; Kimberly A Sanders; Rebecca Carlson; Stefanie P Ferreri
Journal:  Res Social Adm Pharm       Date:  2021-07-16

5.  Economic impact of potentially inappropriate prescribing and related adverse events in older people: a cost-utility analysis using Markov models.

Authors:  Frank Moriarty; Caitriona Cahir; Kathleen Bennett; Tom Fahey
Journal:  BMJ Open       Date:  2019-01-30       Impact factor: 2.692

6.  Development of a Patient-Oriented Intervention to Support Patient-Provider Conversations about Unnecessary Lower Back Pain Imaging.

Authors:  Maryam Madani Larijani; Cindy Dumba; Heather Thiessen; Angie Palen; Tracey Carr; Jason R Vanstone; Daryl R Fourney; Collin Hartness; Robert Parker; Gary Groot
Journal:  Int J Environ Res Public Health       Date:  2021-03-09       Impact factor: 3.390

7.  Addressing Barriers to Reducing Prescribing and Implementing Deprescribing of Sedative-Hypnotics in Primary Care.

Authors:  Lisa Burry; Justin Turner; Timothy Morgenthaler; Cara Tannenbaum; Hyung J Cho; Evelyn Gathecha; Flora Kisuule; Abi Vijenthira; Christine Soong
Journal:  Ann Pharmacother       Date:  2021-07-23       Impact factor: 3.154

  7 in total

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