Literature DB >> 12511871

Is proteomics heading in the wrong direction?

Lukas A Huber1.   

Abstract

Proteomics is now considered to be one of the most important 'post-genome' approaches to help us understand gene function. In fact, several genomics companies have launched large-scale proteomics projects, and have started to annotate the entire human proteome. The 'holistic view' painted by a human proteome project is seductive, but is it realistic?

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Year:  2003        PMID： 12511871     DOI： 10.1038/nrm1007

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN： 1471-0072            Impact factor:   94.444


  18 in total

1.  Protein identification: the origins of peptide mass fingerprinting.

Authors:  William J Henzel; Colin Watanabe; John T Stults
Journal:  J Am Soc Mass Spectrom       Date:  2003-09       Impact factor: 3.109

Review 2.  Proteomics of the human placenta: promises and realities.

Authors:  J M Robinson; W E Ackerman; D A Kniss; T Takizawa; D D Vandré
Journal:  Placenta       Date:  2008-01-28       Impact factor: 3.481

Review 3.  Understanding protein phosphorylation on a systems level.

Authors:  Jimmy Lin; Zhi Xie; Heng Zhu; Jiang Qian
Journal:  Brief Funct Genomics       Date:  2010-01-07       Impact factor: 4.241

4.  In vivo proteomic imaging analysis of caveolae reveals pumping system to penetrate solid tumors.

Authors:  Phil Oh; Jacqueline E Testa; Per Borgstrom; Halina Witkiewicz; Yan Li; Jan E Schnitzer
Journal:  Nat Med       Date:  2014-08-17       Impact factor: 53.440

Review 5.  Receptor tyrosine kinase signaling--a proteomic perspective.

Authors:  Jordane Biarc; Robert J Chalkley; A L Burlingame; Ralph A Bradshaw
Journal:  Adv Enzyme Regul       Date:  2010-11-05

6.  Placental proteomics: a shortcut to biological insight.

Authors:  J M Robinson; D D Vandré; W E Ackerman
Journal:  Placenta       Date:  2008-12-13       Impact factor: 3.481

Review 7.  Peptide motifs: building the clathrin machinery.

Authors:  Peter S McPherson; Brigitte Ritter
Journal:  Mol Neurobiol       Date:  2005-08       Impact factor: 5.590

8.  Proteomics: challenges, techniques and possibilities to overcome biological sample complexity.

Authors:  Kondethimmanahalli Chandramouli; Pei-Yuan Qian
Journal:  Hum Genomics Proteomics       Date:  2009-12-08

9.  Subcellular fractionation enhances proteome coverage of pancreatic duct cells.

Authors:  Joao A Paulo; Aleksandr Gaun; Vivek Kadiyala; Ali Ghoulidi; Peter A Banks; Darwin L Conwell; Hanno Steen
Journal:  Biochim Biophys Acta       Date:  2013-01-22

10.  Isolation of highly enriched apical plasma membranes of the placental syncytiotrophoblast.

Authors:  John M Robinson; William E Ackerman; Arun K Tewari; Douglas A Kniss; Dale D Vandre
Journal:  Anal Biochem       Date:  2009-01-19       Impact factor: 3.365
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