Literature DB >> 1250864

Effect of quality and quantity of dietary fat and dimethylhydrazine in colon carcinogenesis in rats.

B S Reddy, T Narisawa, D Vukusich, J H Weisburger, E L Wynder.   

Abstract

The effect, quality, and quantity of dietary fat on colon tumor induction by DMH were studied in rats exposed to a given regimen for two generations prior to treatment with DMH. Animals fed a 20% corn oil or 20% lard and treated with DMH had a higher incidence of colonic tumors than did rats fed a 5% corn oil, 5% lard or Purina lab chow and treated similarly. The quality of fat had no major difference on the incidence of colonic tumors.

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Year:  1976        PMID: 1250864     DOI: 10.3181/00379727-151-39181

Source DB:  PubMed          Journal:  Proc Soc Exp Biol Med        ISSN: 0037-9727


  16 in total

1.  Colorectal adenomas and diet: a case-control study. Colorectal Adenoma Study Group.

Authors:  B Breuer-Katschinski; K Nemes; A Marr; B Rump; B Leiendecker; N Breuer; H Goebell
Journal:  Dig Dis Sci       Date:  2001-01       Impact factor: 3.199

2.  Potential of magnetic resonance spectroscopy in assessing the effect of fatty acids on inflammatory bowel disease in an animal model.

Authors:  Sonal Varma; Michael N A Eskin; Ranjana Bird; Brion Dolenko; Jayadev Raju; Omkar B Ijare; Tedros Bezabeh
Journal:  Lipids       Date:  2010-08-19       Impact factor: 1.880

3.  Rodent models for carcinoma of the colon.

Authors:  A E Rogers; K M Nauss
Journal:  Dig Dis Sci       Date:  1985-12       Impact factor: 3.199

4.  Repair kinetics of acrolein- and (E)-4-hydroxy-2-nonenal-derived DNA adducts in human colon cell extracts.

Authors:  Sujata Choudhury; Marcin Dyba; Jishen Pan; Rabindra Roy; Fung-Lung Chung
Journal:  Mutat Res       Date:  2013-10-08       Impact factor: 2.433

Review 5.  Chemoprevention of colon cancer by dietary fatty acids.

Authors:  B S Reddy
Journal:  Cancer Metastasis Rev       Date:  1994-12       Impact factor: 9.264

6.  Mortality analysis of colorectal carcinoma in Ireland. Time trends and an international comparison.

Authors:  K Harkin; B MacMahon; J S Doyle; I A Kinsella
Journal:  Ir J Med Sci       Date:  1985-09       Impact factor: 1.568

7.  Morphological and cell kinetic effects of dietary manipulation during colorectal carcinogenesis.

Authors:  D J Galloway; F Jarrett; P Boyle; M Indran; K Carr; R W Owen; W D George
Journal:  Gut       Date:  1987-06       Impact factor: 23.059

8.  Evidence for an adenoma-carcinoma sequence in dimethylhydrazine-induced neoplasms of rat intestinal epithelium.

Authors:  J L Madara; P Harte; J Deasy; D Ross; S Lahey; G Steele
Journal:  Am J Pathol       Date:  1983-02       Impact factor: 4.307

Review 9.  Dietary fat and colon cancer: animal model studies.

Authors:  B S Reddy
Journal:  Lipids       Date:  1992-10       Impact factor: 1.880

10.  Effect of bile acids and dietary fat on large bowel carcinogenesis in animal models.

Authors:  T Narisawa; B S Reddy; J H Weisburger
Journal:  Gastroenterol Jpn       Date:  1978
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