Literature DB >> 12508631

Topical phenytoin in diabetic ulcers: a double blind controlled trial.

M R Pai, N Sitaraman, M S Kotian.   

Abstract

Data of 57 patients who completed the trial and 13 who did not, were analysed. With phenytoin, there was a marginal: increase in the reduction of mean ulcer area and acceleration of effect 3rd on 4th week. With control: the number completing the trial was larger: response to treatment was better in grade II ulcers, Table IV. This study has the hall marks of a real clinical trial, has raised the possibility of wound healing properties of phenytoin and confirms the results of others.

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Year:  2001        PMID: 12508631

Source DB:  PubMed          Journal:  Indian J Med Sci        ISSN: 0019-5359


  4 in total

Review 1.  The application of phenytoin in the treatment of diabetic ulcers.

Authors:  Yi-Shan Liu; Tzong-Shiun Li; Cheuk-Kwan Sun; Kai-Che Wei; Chia-Ju Liu
Journal:  Int Wound J       Date:  2015-10-28       Impact factor: 3.315

2.  Australian guideline on wound healing interventions to enhance healing of foot ulcers: part of the 2021 Australian evidence-based guidelines for diabetes-related foot disease.

Authors:  Pamela Chen; Keryln Carville; Terry Swanson; Peter A Lazzarini; James Charles; Jane Cheney; Jenny Prentice
Journal:  J Foot Ankle Res       Date:  2022-05-25       Impact factor: 3.050

3.  Topical Phenytoin Application in Grade I and II Diabetic Foot Ulcers: A Prospective Study.

Authors:  Vijaya Patil; Rashmi Patil; P L Kariholu; L S Patil; Praveeen Shahapur
Journal:  J Clin Diagn Res       Date:  2013-10-05

Review 4.  Topical phenytoin for treating pressure ulcers.

Authors:  Xiang Yong Hao; Hong Ling Li; He Su; Hui Cai; Tian Kang Guo; Ruifeng Liu; Lei Jiang; Yan Fei Shen
Journal:  Cochrane Database Syst Rev       Date:  2017-02-22
  4 in total

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