BACKGROUND: Impulsivity is prominent in bipolar disorder, but there is little quantitative information relating it to phase of illness. METHODS: We measured impulsivity in patients with bipolar disorder who had not met episode criteria for at least 6 months, patients who were manic, and healthy control subjects. Impulsivity was measured using the Barratt Impulsiveness Scale (BIS) and performance on the computerized Immediate Memory-Remote Memory Task (IMT-DMT), based on the Continuous Performance Test, which has been shown to reflect risk of impulsivity in other populations. RESULTS: BIS scores in euthymic and manic bipolar subjects were identical, and were significantly elevated compared to controls. Commission errors (impulsive responses) on the IMT-DMT were elevated in manic subjects but were identical to controls in euthymic subjects. Measures of impulsivity did not appear related to depressive symptoms. LIMITATIONS: The number of subjects was too small for detailed investigation of the role of comorbidities; subjects were receiving pharmacological treatments. CONCLUSIONS: Impulsivity has state- and trait-related aspects in bipolar disorder.
BACKGROUND: Impulsivity is prominent in bipolar disorder, but there is little quantitative information relating it to phase of illness. METHODS: We measured impulsivity in patients with bipolar disorder who had not met episode criteria for at least 6 months, patients who were manic, and healthy control subjects. Impulsivity was measured using the Barratt Impulsiveness Scale (BIS) and performance on the computerized Immediate Memory-Remote Memory Task (IMT-DMT), based on the Continuous Performance Test, which has been shown to reflect risk of impulsivity in other populations. RESULTS: BIS scores in euthymic and manic bipolar subjects were identical, and were significantly elevated compared to controls. Commission errors (impulsive responses) on the IMT-DMT were elevated in manic subjects but were identical to controls in euthymic subjects. Measures of impulsivity did not appear related to depressive symptoms. LIMITATIONS: The number of subjects was too small for detailed investigation of the role of comorbidities; subjects were receiving pharmacological treatments. CONCLUSIONS: Impulsivity has state- and trait-related aspects in bipolar disorder.
Authors: Michael A Cerullo; Caleb M Adler; Martine Lamy; James C Eliassen; David E Fleck; Stephen M Strakowski; Melissa P DelBello Journal: Early Interv Psychiatry Date: 2009-08 Impact factor: 2.732
Authors: Christen M Deveney; Megan E Connolly; Sarah E Jenkins; Pilyoung Kim; Stephen J Fromm; Daniel S Pine; Ellen Leibenluft Journal: Biol Psychol Date: 2011-10-18 Impact factor: 3.251
Authors: Natania A Crane; Alvaro Vergés; Masoud Kamali; Runa Bhaumik; Kelly A Ryan; David F Marshall; Erika F H Saunders; Michelle T Kassel; Anne L Weldon; Melvin G McInnis; Scott A Langenecker Journal: Assessment Date: 2018-02-06
Authors: Chelsea L Black; Kim E Goldstein; Denise R LaBelle; Christopher W Brown; Eddie Harmon-Jones; Lyn Y Abramson; Lauren B Alloy Journal: Behav Ther Date: 2014-01-30
Authors: Birgit Abler; Ian Greenhouse; Dost Ongur; Henrik Walter; Stephan Heckers Journal: Neuropsychopharmacology Date: 2007-11-07 Impact factor: 7.853