Literature DB >> 12505550

P300 amplitude in subjects with primary insomnia is modulated by their sleep quality.

Alessandra Devoto1, Cristiano Violani, Fabio Lucidi, Caterina Lombardo.   

Abstract

OBJECTIVE: The hyperarousal hypothesis is evaluated while controlling the influence of the quality of sleep in the night preceding the evaluation.
METHOD: Eleven primary insomniacs and 11 healthy age matched controls participated to the study. Participants filled in 2 weeks of sleep logs and self-monitored their subjective tension the evening before and the morning after each night. Afterwards, subjects were called in to the Lab for a recording session of the P300 ERP (oddball paradigm) once after a night of bad sleep quality (N-) and once after a night of good sleep quality (N+).
RESULTS: The main result of the present study indicated that the P300 amplitude at Fz in insomniacs resulted higher following a N- and lower following a N+ with respect to controls.
CONCLUSIONS: This result suggests that cortical hyperarousal in primary insomniacs is not a stable individual characteristic, but is associated with the poor quality of their nocturnal sleep. Copyright 2003 Elsevier Science Inc.

Entities:  

Mesh:

Year:  2003        PMID: 12505550     DOI: 10.1016/s0022-3999(02)00579-2

Source DB:  PubMed          Journal:  J Psychosom Res        ISSN: 0022-3999            Impact factor:   3.006


  10 in total

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